Results 101 to 110 of about 1,446 (177)

Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population

open access: yesGenomics Data, 2017
Our group recently employed genome-wide transcriptional profiling in tandem with machine-learning based analysis to identify a ten-gene pattern of differential expression in peripheral blood which may have utility for detection of stroke.
Grant C. O'Connell   +2 more
doaj   +1 more source

Broad expression analysis of human ANTXR1/TEM8 transcripts reveals differential expression and novel splizce variants.

open access: yesPLoS ONE, 2012
Tumor endothelial marker 8 (TEM8; ANTXR1) is one of two anthrax toxin receptors; the other is capillary morphogenesis gene 2 protein (CMG2; ANTXR2).
Micaela Vargas   +3 more
doaj   +1 more source

Identification of key genes and upstream regulators in ischemic stroke

open access: yesBrain and Behavior, 2019
Introduction Ischemic stroke (IS) causes severe neurological impairments and physical disabilities and has a high economic burden. Our study aims to identify the key genes and upstream regulators in IS by integrated microarray analysis.
Qian Zhang   +5 more
doaj   +1 more source

Airway characteristics in a hyaline fibromatosis syndrome patient and the role of a difficult airway clinic – A case report

open access: yesJCA Advances
Hyaline Fibromatosis Syndrome (HFS) is a rare autosomal recessive disorder caused by mutations in the ANTXR2 gene. It is characterized by abnormal deposition of hyaline material in skin, mucosa, joints, and other tissues.
Muhammad Jaffar Khan, MBBS, EDAIC   +4 more
doaj   +1 more source

Abstracts

open access: yes
Cancer Science, Volume 116, Issue S1, Page 1-1975, January 2025.
wiley   +1 more source

Host Cell Transcriptional Tuning with CRISPR/dCas9 to Mitigate the Effects of Toxin Exposure

open access: yes
Anthrax infection is caused byBacillus anthracis, a bacterium that once established within the host releases lethal toxin (LeTx). Anthrax LeTx is internalized by the capillary morphogenesis protein 2/anthrax toxin receptor 2 (CMG2/ANTXR2) cell surface ...
David Metzger (3750670)   +5 more
core   +1 more source

Anthrax toxin receptor 2 gene (ANTXR2) rs4333130 is associated with ankylosing spondylitis.

open access: yesInternational journal of clinical and experimental medicine, 2015
Results of recent published studies on the association between the ANTXR2 rs4333130 polymorphism and the risk of ankylosing spondylitis (AS) have often been conflicting. To make a more precise estimation of the potential relationship, a meta-analysis was performed.
openaire   +1 more source

Bacillus anthracis: una mirada molecular a un patógeno célebre Bacillus anthracis: a molecular look at a famous pathogen

open access: yesRevista Argentina de Microbiología, 2011
Bacillus anthracis es un bacilo gram positivo del grupo Bacillus cereus, que posee un genoma extremadamente monomórfco y comparte gran similitud fsiológica y de estructura genética con B. cereus y Bacillus thuringiensis.
María E Pavan   +4 more
doaj  

Cathepsin B-mediated Autophagy Flux Facilitates the Anthrax Toxin Receptor 2-mediated Delivery of Anthrax Lethal Factor into the Cytoplasm [PDF]

open access: yes, 2010
Anthrax lethal toxin (LeTx) is a virulence factor secreted by Bacillus anthracis and has direct cytotoxic effects on most cells once released into the cytoplasm. The cytoplasmic delivery of the proteolytically active component of LeTx, lethal factor (LF),
林圣彩   +6 more
core  

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