Results 81 to 90 of about 1,446 (177)

Genome‐wide population affinities and signatures of adaptation in hydruntines, sussemiones and Asian wild asses

Molecular Ecology, Volume 33, Issue 19, October 2024.
Abstract The extremely rich palaeontological record of the horse family, also known as equids, has provided many examples of macroevolutionary change over the last ~55 Mya. This family is also one of the most documented at the palaeogenomic level, with hundreds of ancient genomes sequenced.
Jianfei Pan, Xuexue Liu, Mateusz Baca, Laure Calvière‐Tonasso, Stéphanie Schiavinato, Loreleï Chauvey, Gaétan Tressières, Aude Perdereau, Jean‐Marc Aury, Pedro H. Oliveira, Patrick Wincker, Aida Abdykanova, Juan Luis Arsuaga, Jamsranjav Bayarsaikhan, Andrey B. Belinskiy, Eudald Carbonell, Hossein Davoudi, Jaime Lira Garrido, Allan S. Gilbert, Taylor Hermes, Christina Warinner, Alexey A. Kalmykov, David Lordkipanidze, Paweł Mackiewicz, Azadeh F. Mohaseb, Kristine Richter, Nuritdin Sayfullaev, Beth Shapiro, Svetlana Shnaider, John Southon, Krzysztof Stefaniak, Geoffrey D. Summers, Eline Naomi van Asperen, Nikoloz Vanishvili, Eden A. Hill, Pavel Kuznetsov, Sabine Reinhold, Svend Hansen, Marjan Mashkour, Rémi Berthon, William Timothy Treal Taylor, Jean‐Luc Houle, Evon Hekkala, Danijela Popović, Ludovic Orlando   +44 more
wiley   +1 more source

The cell surface T118A mutant ANTXR2 receptor binds PA.

, 2013
(A) Flow cytometric analysis of PA binding to CHO-R1.1 cells and CHO-R1.1 cells engineered to express WT or mutant ANTXR2-EGFP fusion proteins. The cells were incubated with PA and then with a PA-specific antibody followed by an APC-labeled secondary ...
John A.T. Young (42988), Heather M. Scobie (42987)   +1 more
core   +1 more source

Phagolysosomal resistance hypothesized to be a danger signal

Scandinavian Journal of Immunology, Volume 100, Issue 4, October 2024.
Does the adaptive immune system detect and respond to microbial resistance to innate immune effectors? Is physical linkage between epitopes of pathogenic antigens, an underlying thread running through much of mammalian immune response? Can enzymatic detoxification of reactive oxygen species and nitric oxide work as an adjuvant in vaccines?
Christopher A. Forden
wiley   +1 more source

Case-Control Study and Meta-Analysis Show a Weak Association between ANTXR2 Polymorphisms and Ankylosing Spondylitis in Chinese Han

, 2018
Previous studies have demonstrated associations of ANTXR2 gene polymorphisms with ankylosing spondylitis (AS). These associations differ depending on the ethnic populations and AS subgroups studied.
Yang, Peizeng, Liu, Shengyun, Cao, Qinfeng, Du, Liping, Deng, Jing, Kijlstra, Aize, Hu, Jiayue, Su, Wencheng, Yuan, Gangxiang   +8 more
core   +1 more source

The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin. [PDF]

PLoS ONE, 2010
Anthrax toxin, which is released from the gram-positive bacterium Bacillus anthracis, is composed of three proteins: protective antigen (PA), lethal factor (LF), and edema factor (EF).
Sheng Fu, Xiaohang Tong, Chenguang Cai, Ying Zhao, Yang Wu, Yuanyuan Li, Junjie Xu, Xuejun C Zhang, Long Xu, Wei Chen, Zihe Rao   +10 more
doaj   +1 more source

Identification of novel pQTL‐SNPs associated with lung adenocarcinoma risk: A multi‐stage study

Cancer Medicine, Volume 13, Issue 17, September 2024.
Abstract Background and Objective To explore the association between protein quantitative trait loci (pQTL‐SNPs) and the risk of LUAD. Methods “Blood +” high depth blood proteomics analysis was performed on plasma from female LUAD patients and female healthy controls, and combined with proteomics data from tumors and adjacent non‐tumor tissues of ...
Yutong Wu, Huiwen Xu, Liping Mao, Rongrong Zhao, Junfeng Chu, Lili Huang, Wendi Zhang, Yiran Liu, Qiong Chen, Xiaobo Tao, Siqi Li, Shenxuan Zhou, Anhui Ning, Zhenyu Li, Tian Tian, Lei Zhang, Jiahua Cui, Guangyu Tian, Minjie Chu   +18 more
wiley   +1 more source

Identification of gravity‐responsive serum proteins in spaceflight mice using a quantitative proteomic approach with data‐independent acquisition mass spectrometry

PROTEOMICS, Volume 24, Issue 9, May 2024.
Abstract Physical inactivity associated with gravity unloading, such as microgravity during spaceflight and hindlimb unloading (HU), can cause various physiological changes. In this study, we attempted to identify serum proteins whose levels fluctuated in response to gravity unloading.
Yayoi Kimura, Yusuke Nakai, Yoko Ino, Tomoko Akiyama, Kayano Moriyama, Takashi Ohira, Tomoyuki Saito, Yutaka Inaba, Ken Kumagai, Akihide Ryo, Hisashi Hirano   +10 more
wiley   +1 more source

Characterizing the Biomechanical and Biochemical Properties of Mouse Uterine Tissue [PDF]

, 2020
For a successful pregnancy, the uterus and the cervix work together as a biomechanical structure to protect the fetus until term. During gestation, typically 37 weeks, the uterus undergoes a growth transformation to accommodate the growing fetus and to ...
Yoshida, Kyoko, Meyers, Kristen, Mondragon, Eli   +2 more
core   +1 more source

Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression

Advanced Science, Volume 11, Issue 11, March 20, 2024.
Cell‐extracellular matrix interactions are critical regulators of cancer cell growth and invasion. This study revealed depletion of two collagen‐binding receptors, α1‐ and α2‐integrins, in aggressive forms of prostate cancer. Loss of α1‐ and α2‐integrins triggered an autocrine secretion of TGFβ leading to EMT and elevated metastatic capacity.
Sara P. Cruz, Qin Zhang, Raman Devarajan, Christos Paia, Binjie Luo, Kai Zhang, Saara Koivusalo, Longguang Qin, Jihan Xia, Anne Ahtikoski, Markku Vaarala, Tomasz Wenta, Gong‐Hong Wei, Aki Manninen   +13 more
wiley   +1 more source

Combined analysis of secreted proteins and glycosylation identifies prognostic features in cholangiocarcinoma

Journal of Cellular Physiology, Volume 239, Issue 3, March 2024.
Changes in fucosylation and sialylation were associated with the secretome of metastatic cholangiocarcinoma (CCA). A survival analysis across secreted protein‐coding genes revealed a more favorable prognostic effect when combined with fucosyltransferase‐ or sialyltransferase‐coding genes than when evaluated individually.
Diane Dayoung Park, Gege Xu, Simon S. Park, Nathan E. Haigh, Chatchai Phoomak, Sopit Wongkham, Emanual Maverakis, Carlito B. Lebrilla   +7 more
wiley   +1 more source