Results 61 to 70 of about 1,446 (177)
The Hainan black goat is a high-quality local goat breed in Hainan Province of China. It is resistant to high temperatures, humidity, and disease. Although the meat of this breed is tender and delicious, its reproductive performance and milk yield are ...
Rui HUA +5 more
doaj +1 more source
Abstract INTRODUCTION APOE ε4 is the strongest common genetic risk factor for Alzheimer's disease (AD), yet many carriers remain cognitively unimpaired into late life. We tested whether protected ε4‐first plasma proteomics could identify proteins associated with delayed clinical onset.
Yann Le Guen +3 more
wiley +1 more source
Reduced MMP2 activity in Antxr2 deficient tissue and cells.
(A) Uterine lysates from six-month-old mice, Antxr2+/+ (n = 2) and Antxr2−/− (n = 2), were immunoblotted for MMP2 and demonstrated that there are reduced levels of active MMP2 in the Antxr2−/− tissue (P = the pro form of MMP2, I = the intermediate form ...
Claire V. Reeves (172057) +6 more
core +1 more source
A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. [PDF]
The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B.
Darly J Manayani +12 more
doaj +1 more source
Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin
Bacterial products are able to act on nociceptive neurons during pathogenic infection. Neurogenic inflammation is an active part of pain signaling and has recently been shown to impact host-pathogen defense.
Nicole J. Yang +7 more
doaj +1 more source
ANTXR2 ectodomain is composed of R2-VWA and R2-Ig.
A. Schematic of ANTXR2. ANTXR2 is composed of R2-VWA (VWA, 38–218) and R2-Ig (Ig, 219–318), a single-pass transmembrane domain (TM, 319–343) and a cytoplasmic domain (Cyto, 344–489). B.
Jianjun Sun (54027) +1 more
core +1 more source
Transcriptome‐Based Analysis of Core Hub Genes Related to Cell Adhesion in Vero Cells
The key to constructing suspension cell lines through genetic engineering technology lies in identifying the fundamental components and molecules involved in cell adhesion. In this study, differentially expressed genes between adherent and suspension Vero cells were analyzed using transcriptomics.
Yiyang Fan +8 more
wiley +1 more source
Background Hyaline fibromatosis syndrome (HFS) is a rare clinical condition in which bi-allelic variants in ANTXR2 are associated with extracellular hyaline deposits. It manifests as multiple skin nodules, patchy hyperpigmentation, joint contractures and
Claudia Cozma +15 more
doaj +1 more source
EGFR-PKM2 signaling promotes the metastatic potential of nasopharyngeal carcinoma through induction of FOSL1 and ANTXR2 [PDF]
Abstract Nasopharyngeal carcinoma (NPC) is notorious for its aggressiveness and high metastatic potential. NPC patients with distant metastasis have a particularly poor prognosis; however, evaluating metastatic potential by expression profiles of primary tumors is challenging.
Chen, Shengnan +12 more
openaire +4 more sources
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte +13 more
wiley +1 more source

