Results 61 to 70 of about 1,446 (177)

Studying the variations in differently expressed serum proteins of Hainan black goat during the breeding cycle using isobaric tags for relative and absolute quantitation (iTRAQ) technology

open access: yesThe Journal of Reproduction and Development, 2019
The Hainan black goat is a high-quality local goat breed in Hainan Province of China. It is resistant to high temperatures, humidity, and disease. Although the meat of this breed is tender and delicious, its reproductive performance and milk yield are ...
Rui HUA   +5 more
doaj   +1 more source

Proteomic signatures of protected APOE ε4 carriers reveal causal pathways associated with delayed Alzheimer's disease onset

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION APOE ε4 is the strongest common genetic risk factor for Alzheimer's disease (AD), yet many carriers remain cognitively unimpaired into late life. We tested whether protected ε4‐first plasma proteomics could identify proteins associated with delayed clinical onset.
Yann Le Guen   +3 more
wiley   +1 more source

Reduced MMP2 activity in Antxr2 deficient tissue and cells.

open access: yes, 2012
(A) Uterine lysates from six-month-old mice, Antxr2+/+ (n = 2) and Antxr2−/− (n = 2), were immunoblotted for MMP2 and demonstrated that there are reduced levels of active MMP2 in the Antxr2−/− tissue (P = the pro form of MMP2, I = the intermediate form ...
Claire V. Reeves (172057)   +6 more
core   +1 more source

A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. [PDF]

open access: yesPLoS Pathogens, 2007
The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B.
Darly J Manayani   +12 more
doaj   +1 more source

Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin

open access: yesFrontiers in Immunology, 2021
Bacterial products are able to act on nociceptive neurons during pathogenic infection. Neurogenic inflammation is an active part of pain signaling and has recently been shown to impact host-pathogen defense.
Nicole J. Yang   +7 more
doaj   +1 more source

ANTXR2 ectodomain is composed of R2-VWA and R2-Ig.

open access: yes, 2013
A. Schematic of ANTXR2. ANTXR2 is composed of R2-VWA (VWA, 38–218) and R2-Ig (Ig, 219–318), a single-pass transmembrane domain (TM, 319–343) and a cytoplasmic domain (Cyto, 344–489). B.
Jianjun Sun (54027)   +1 more
core   +1 more source

Transcriptome‐Based Analysis of Core Hub Genes Related to Cell Adhesion in Vero Cells

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
The key to constructing suspension cell lines through genetic engineering technology lies in identifying the fundamental components and molecules involved in cell adhesion. In this study, differentially expressed genes between adherent and suspension Vero cells were analyzed using transcriptomics.
Yiyang Fan   +8 more
wiley   +1 more source

Genetic, clinical and biochemical characterization of a large cohort of patients with hyaline fibromatosis syndrome

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Hyaline fibromatosis syndrome (HFS) is a rare clinical condition in which bi-allelic variants in ANTXR2 are associated with extracellular hyaline deposits. It manifests as multiple skin nodules, patchy hyperpigmentation, joint contractures and
Claudia Cozma   +15 more
doaj   +1 more source

EGFR-PKM2 signaling promotes the metastatic potential of nasopharyngeal carcinoma through induction of FOSL1 and ANTXR2 [PDF]

open access: yesCarcinogenesis, 2019
Abstract Nasopharyngeal carcinoma (NPC) is notorious for its aggressiveness and high metastatic potential. NPC patients with distant metastasis have a particularly poor prognosis; however, evaluating metastatic potential by expression profiles of primary tumors is challenging.
Chen, Shengnan   +12 more
openaire   +4 more sources

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1528-1547, August 2025.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte   +13 more
wiley   +1 more source

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