Results 121 to 130 of about 234,054 (170)
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Rheumatoid Arthritis — Anti-TNF
International Immunopharmacology, 2015This review will focus on the recent information and strategies now informing best use of TNF inhibitor therapy in RA. These issues include the role of TNFi therapy in early RA management, anti-drug antibodies in TNFi therapy, updates on safety and optimal dosage regimens in long term management.
Khaldoun, Chaabo, Bruce, Kirkham
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Safety of anti-TNF agents in pregnancy
Journal of Allergy and Clinical Immunology, 2021Inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and psoriasis are associated with adverse pregnancy outcomes. Active maternal disease during pregnancy is associated with additional negative outcomes. Anti-TNF agents are effective treatments for inflammatory bowel disease, rheumatoid arthritis, ankylosing ...
Kara M, De Felice, Sunanda, Kane
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Anti-TNFs in axial spondyloarthritis
Wiener Medizinische Wochenschrift, 2015Since there is no evidence regarding the efficacy of conventional synthetic disease modifying anti-rheumatic drugs in the improvement of axial spondyloarthritis (SpA), anti-tumor necrosis factors (anti-TNFs) are recommended if nonsteroidal anti-inflammatory drugs fail, or in case of high disease activity.
Roland, Kocijan +2 more
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Anti-TNFs: Originators and Biosimilars
Digestive Diseases, 2016In the last 20 years, the advent of anti-tumor necrosis factor alpha (TNFα) biologics has revolutionized the treatment of patients with inflammatory bowel disease (IBD) but the cost of biologic therapy now constitutes a large proportion of all healthcare expenditures. Patent expiration has sparked the healthcare industry's interest in the production of
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Reumatología Clínica (English Edition), 2010
Tumor necrosis factor (TNF) is implicated in the control of tumoral growth in addition to the systemic inflammatory response. TNF blockage produces a comprensible reservation in patients with risk factors for cancer. No clear evidence for this came out from pre-clinical or clinical trials.
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Tumor necrosis factor (TNF) is implicated in the control of tumoral growth in addition to the systemic inflammatory response. TNF blockage produces a comprensible reservation in patients with risk factors for cancer. No clear evidence for this came out from pre-clinical or clinical trials.
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Anti-TNF agents for the treatment of spondyloarthropathies
Expert Opinion on Emerging Drugs, 2002For the treatment of spondyloarthropathies (SpA), therapeutic options using disease-modifying drugs are rather limited compared to other inflammatory rheumatic diseases such as rheumatoid arthritis (RA). This is especially true for the spinal symptoms of the spondyloarthropathies, of which ankylosing spondylitis (AS) is the prototype.
Joachim, Sieper, Jürgen, Braun
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Anti‐TNF alpha medications and neuropathy
Journal of the Peripheral Nervous System, 2015AbstractWe studied the clinical, electrophysiological, and pathological features, outcome, and frequency of anti‐tumor necrosis factor alpha (a‐TNF) medications‐induced neuropathies (ATIN) in patients with inflammatory disorders. Of 2,017 patients treated with a‐TNF medication, 12 patients met our inclusion criteria for a prevalence of 0.60% and an ...
Tsouni, P. +6 more
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Sepsis, 1999
Monoclonal antibodies to tumor necrosis factor alpha (TNF-α) and soluble receptor complexes comprising the extramembrane portion of the TNF receptor coupled with the Fc portion of the human IgG1 molecule have been utilized as therapies for severe sepsis and septic shock.
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Monoclonal antibodies to tumor necrosis factor alpha (TNF-α) and soluble receptor complexes comprising the extramembrane portion of the TNF receptor coupled with the Fc portion of the human IgG1 molecule have been utilized as therapies for severe sepsis and septic shock.
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The ‘Ideal' Anti-TNF Patient: Indications for Anti-TNF Therapy in Crohn's Disease
2015The introduction of anti-TNF monoclonal antibodies to the therapeutic arsenal has represented a major advance in the management of Crohn's disease (CD).
My-Linh Tran-Minh +2 more
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Anti - TNF Therapy for Crohns Disease
Current Pharmaceutical Design, 2003Although the cause of Crohn's disease remains unknown considerable progress has been made in recent years to unravel the pathogenesis of the inflammatory processes seen in chronic idiopathic inflammatory bowel diseases (IBD). Th-1 lymphocytes seem to orchestrate the inflammation through the production of pro-inflammatory cytokines such as IFN-gamma, IL-
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