Results 121 to 130 of about 12,749 (324)

Topical imiquimod and in situ vulvar melanoma: A promising therapy?

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Vulvar melanoma is a rare type of cancer that affects mainly postmenopausal women. There are no established protocols for the treatment of vulvar melanoma. From data extrapolated from the literature on cutaneous melanoma, surgical excision remains the best option for the resectable disease.
Francesca Pepe, Flavia Silvestri, Eleonora Petra Preti, Anna Daniela Iacobone, Gianluigi Radici, Sabina Vaccari, Paola Queirolo, Giulio Tosti   +7 more
wiley   +1 more source

Perspective: Speculative role of Tmp21 mediated protein secretory pathway during endoplasmic reticulum (ER) stress induced chronic inflammation [PDF]

arXiv, 2016
By deploying myelofibrosis as the disease context, I wish to propose that increased availability of Tmp21 (an NFAT gene target) induces aberrant protein secretion from the ER contributing to pathological consequences, which has not been elucidated before.
arxiv  

Percutaneous Transretropubic Needle Prostatic Biopsy Under US and CT Guidance

IJU Case Reports, EarlyView.
ABSTRACT Introduction No previous instances of percutaneous transretropubic prostate biopsy have been documented. Case Presentation A 74‐year‐old male patient with a permanent stoma, who had undergone colectomy for descending colon cancer two decades earlier, reported experiencing dysuria.
Maki Hirao, Hideki Ishimaru, Satomi Yoshimi, Takamasa Nishimura, Taiga Oka, Chika Somagawa, Tomoki Nakano, Ryoichi Imamura, Ryo Toya   +8 more
wiley   +1 more source

Forecasting Leading Death Causes in Australia using Extended CreditRisk$+$ [PDF]

arXiv, 2015
Recently we developed a new framework in Hirz et al (2015) to model stochastic mortality using extended CreditRisk$^+$ methodology which is very different from traditional time series methods used for mortality modelling previously. In this framework, deaths are driven by common latent stochastic risk factors which may be interpreted as death causes ...
arxiv  

The value of flexible sigmoidoscopy for patients with bright red rectal bleeding [PDF]

, 2003
Objective. To review the diagnostic yield of flexible sigmoidoscopy in patients presenting with bright red rectal bleeding. Design. Retrospective study. Setting. University teaching hospital, Hong Kong. Subjects and methods.
Choi, HK, Chu, KW, Law, WL
core  

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

iMetaOmics, EarlyView.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan, Xiaoli Zhang, Ling Zhou, Xiaoya Zhao, Qianniu Li, Tian Lan, Jun Fu, Jingyun Ma   +7 more
wiley   +1 more source

Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV

Acta Oncologica
Background/purpose: To investigate if pre-treatment tumour positron-emission tomography (PET) metrics’ prognostic efficacy changes with HIV or viral load (VL) in anal squamous cell carcinoma (ASCC).
Michael Pennock, N. Patrik Brodin, Christian Velten, Megi Gjini, Nitin Ohri, Chandan Guha, Shalom Kalnicki, Wolfgang A. Tome, Madhur K. Garg, Rafi Kabarriti   +9 more
doaj   +1 more source

Evaluation of the scope, quality, and health literacy demand of Internet-based anal cancer information

Journal of the Medical Library Association, 2019
Objectives: As there is a dearth of information about anal cancer available at cancer centres, patients often use the Internet to search for information.
Rebecca Charow, Michelle Snow, Sameera Fathima, Meredith E. Giuliani, Kate McEwan, Jordana Winegust, Janet Papadakos   +6 more
doaj   +1 more source

Explainable machine learning for neoplasms diagnosis via electrocardiograms: an externally validated study [PDF]

arXiv
Background: Neoplasms remains a leading cause of mortality worldwide, with timely diagnosis being crucial for improving patient outcomes. Current diagnostic methods are often invasive, costly, and inaccessible to many populations. Electrocardiogram (ECG) data, widely available and non-invasive, has the potential to serve as a tool for neoplasms ...
arxiv  

Deep Multi-Modal Classification of Intraductal Papillary Mucinous Neoplasms (IPMN) with Canonical Correlation Analysis [PDF]

arXiv, 2017
Pancreatic cancer has the poorest prognosis among all cancer types. Intraductal Papillary Mucinous Neoplasms (IPMNs) are radiographically identifiable precursors to pancreatic cancer; hence, early detection and precise risk assessment of IPMN are vital.
arxiv