Results 141 to 150 of about 18,052 (236)

Solitary Fibrous Tumor of the Mesentery of the Small Intestine: A Rare Case Report. [PDF]

J Anus Rectum Colon
Ito G, Hattori K, Ota Y, Mukohyama J, Sakuyama N, Shida D.   +5 more
europepmc   +1 more source

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

Metastatic Anal Fistula Carcinoma after Rectosigmoid Cancer Surgery Treated with Robot-Assisted Abdominoperineal Resection and Gluteal Myocutaneous Flap Reconstruction: A Case Report. [PDF]

Surg Case Rep
Kunitomo A, Matsumura T, Shinohara K, Fukami Y, Kaneko K, Komatsu S, Takahashi E, Tsuzuki T, Sano T.   +8 more
europepmc   +1 more source

Targeting Human Protein Kinase CK2 by a Library of Indeno[1,2‐b]Indoles: Contribution of Thermal Shift Assay to Pre‐Screening and Co‐Crystallization to Post‐Screening

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
A series of 25 functionalized indeno[1,2‐b]indoles was selected from in‐house compound library and additional synthesis work. Capillary electrophoresis‐based and thermal shift assays, X‐ray analysis of small molecules, and co‐crystallization studies highlighted a key molecular template for the inhibitory potential of protein kinase CK2.
Matheus M. Guimarães, Christian Werner, Belen Leroy, Johana Charles, Jean Guillon, Noël Pinaud, Angélique Mularoni, Marc Jean‐Baptiste, Perrine Ximenes, Alexander Gast, Helge Prinz, Dagmar Aichele, Alan G. Gonçalves, Christelle Marminon, Zouhair Bouaziz, Joachim Jose, Jean‐Guy Delcros, Karsten Niefind, Marc Le Borgne   +18 more
wiley   +1 more source

Case Report: Definitive radiotherapy for inoperable anal Buschke-Löwenstein tumors: two cases with literature review. [PDF]

Front Oncol
Ben Rejeb M, Abdessatar G, Mlayah I, Saadi M, Mejri N, Kochbati L.   +5 more
europepmc   +1 more source

Comparative Cardiovascular Safety and Exploratory Bleeding Outcomes of Ibrutinib, Acalabrutinib, and Zanubrutinib in Mantle Cell Lymphoma: A Propensity Score‐Matched Real‐World Analysis

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Bruton tyrosine kinase inhibitors are central to the treatment of relapsed or refractory mantle cell lymphoma, but cardiovascular and bleeding toxicities influence treatment selection. Ibrutinib has been associated with atrial fibrillation/flutter and other cardiovascular adverse events, whereas second‐generation covalent BTK ...
Anna Homeniuk, Amrit Sandhu, Leena Abdalla, Anas Atrash   +3 more
wiley   +1 more source

Surgical treatment of a congenital rectal cystic hamartoma in a 20-day Kurdish foal. [PDF]

Vet Res Forum
Azizi S, Mahmoudi SS, Shamsi Z, Akbari M, Azizi D.   +4 more
europepmc   +1 more source

A Comprehensive Meta‐Analysis and Review of Intraoperative Radiotherapy in Colorectal Cancer: Examining Radiation Dosage, Long‐Term Prognosis, and Treatment‐Related Complications

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background The effect of device type and radiation dose in intraoperative radiotherapy (IORT) for colorectal cancer is not well established. To explore this, we reviewed studies reporting postoperative complications, disease‐free survival, local control, and long‐term survival in patients treated with non‐implantable IORT techniques—IOERT, KV ...
Chuhan Guo, Shuyang Liu, Liangliang Li, Jiayi Zhao, Hongji Zhou, Hongqiang Liu, Tong Liu, Fujian Ji   +7 more
wiley   +1 more source

Case Report: Integration of intratumoral oncolytic adenovirus with total neoadjuvant therapy in metachronous locally advanced rectal cancer. [PDF]

Front Oncol
Chen X, Zhao Z, Chen Z, Li W, Sun H.
europepmc   +1 more source

Comparison of Thrombocytopenia and Splenomegaly in Locally Advanced Rectal Cancer Patients Receiving Total Neoadjuvant Therapy With and Without Immunotherapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Thrombocytopenia is a common toxicity of oxaliplatin‐based chemotherapy and may be linked to hepatic sinusoidal obstruction and splenic enlargement. In the TORCH trial, adding PD‐1 blockade to an oxaliplatin‐containing total neoadjuvant therapy (TNT) regimen improved tumor response in patients with locally advanced rectal cancer ...
Shuwen Li, Mingxu Yan, Qiong Ma, Yiqun Sun, Zhen Zhang, Lijun Shen, Juefeng Wan, Hui Zhang, Ruiyan Wu, Fan Xia, Yaqi Wang   +10 more
wiley   +1 more source