Results 131 to 140 of about 21,652 (281)
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino +5 more
wiley +1 more source
Squamous anal cell carcinoma frequency has been changing during the last decades. It was a rare disease in the past with 0.2 cases per 100,000 inhabitants in Denmark before the 60’s and 0.5 per 100,000 in the United States of America (USA) in 1973 ...
José Ricardo Hildebrandt Coutinho
doaj +1 more source
ABSTRACT Aim This study aimed to evaluate point‐of‐care ultrasound (POCUS) findings in children with functional constipation who achieved complete clinical improvement following standard treatment in accordance with international guidelines. Material and Methods The study included 58 children (31 boys) aged 0.9–16.1 (mean age 5.22 ± 3.24), diagnosed ...
Martyna Laskowska +5 more
wiley +1 more source
One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard +13 more
wiley +1 more source
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis +9 more
wiley +1 more source
Konzeptionelle und empirische Fragen der Krankheitsauswahl im Kontext der Einführung des morbiditätsorientierten Risikostrukturausgleichs in der GKV [PDF]
Gemäß § 31 Abs. 1 Risikostrukturausgleichs-Verordnung (RSAV) soll sich das Versichertenklassifikationsmodell für den morbiditätsorientierten RSA an 50-80 Krankheiten orientieren.
Dahl, Helmut +4 more
core
Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics
ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon +3 more
wiley +1 more source
Descriptive Evaluation of Patient Characteristics and Health Care Resource Utilization of Patients Diagonsed with Malignant Neoplasm of Anus [PDF]
Greene, N, Greene, M
openaire +2 more sources

