Results 31 to 40 of about 798,677 (318)

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Eser, Daniela, Eser D., Baghai, Thomas C., Schule C., Romeo, Elena, Baghai T. C., Schuele, Cornelius, Rupprecht R., Rupprecht, Rainer, Eser D., Schule C., Baghai T.C., Romeo E., Rupprecht R.   +9 more
core   +1 more source

Help from home for depression: A randomised controlled trial comparing internet-delivered cognitive behaviour therapy with bibliotherapy for depression

Internet Interventions, 2017
Major Depressive Disorder (MDD) is a leading cause of the Global Burden of Disease. Cognitive Behavioural Therapy (CBT) is an effective treatment for MDD, but access can be impaired due to numerous barriers.
Jessica Smith, Jill M. Newby, Nicole Burston, Michael J. Murphy, Sarah Michael, Anna Mackenzie, Felicity Kiln, Siobhan A. Loughnan, Kathleen A. O'Moore, Benjamin J. Allard, Alishia D. Williams, Gavin Andrews   +11 more
doaj   +1 more source

Somatic symptoms of generalized anxiety disorder from the DSM-IV: Associations with pathological worry and depression symptoms in a nonclinical sample [PDF]

, 1999
The present study investigates specificity of the six somatic symptoms that are associated with generalized anxiety disorder (GAD), according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders.
Joormann, Jutta, Stoeber, Joachim, Joachim Stöber, Jutta Joormann   +3 more
core   +1 more source

Intensive one-week internet-delivered cognitive behavioral therapy for panic disorder and agoraphobia: A pilot study

Internet Interventions, 2020
This is the first pilot study to explore the feasibility, acceptability and preliminary efficacy of intensive cognitive behavioral therapy (CBT) for panic disorder and/or agoraphobia delivered via the internet. Ten participants who met DSM-5 criteria for
Eileen P. Stech, Ashlee B. Grierson, Aileen Z. Chen, Maria J. Sharrock, Alison E.J. Mahoney, Jill M. Newby   +5 more
doaj   +1 more source

Prospective longitudinal associations between persistent sleep problems in childhood and anxiety and depression disorders in adulthood

, 2005
The objective of this study was to examine the associations between persistent childhood sleep problems and adulthood anxiety and depression. Parents of 943 children (52% male) participating in the Dunedin Multidisciplinary Health and Development Study ...
Caspi, Avshalom, Eley, Thalia C., Avshalom Caspi, O'Connor, Thomas G., Thalia C. Eley, Thomas G. O’connor, Poulton, Richie, Terrie E, Poulton, R, Gregory, A M, Moffitt, T E; id_orcid, O'Connor, T G, Moffitt, Terrie E., Eley, T C, Gregory, Alice M., Caspi, A, Richie Poulton, Alice M. Gregory   +17 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Traumatic stress alters neural reactivity to visual stimulation

NPP-Digital Psychiatry and Neuroscience
Traumatic stress is a precursor to the development of posttraumatic stress disorder (PTSD). Emergent research suggests visual processing regions may be relevant to PTSD development; however, no previous research to date has investigated the potential ...
Nathaniel G. Harnett, Grace E. Rowland, E. Kate Webb, Tianyi Li, Soumyaa Joshi, Kerry J. Ressler, Isabelle M. Rosso   +6 more
doaj   +1 more source

Outcomes for depression and anxiety in primary care and details of treatment: a naturalistic longitudinal study

, 2011
Background There is little evidence as to whether or not guideline concordant care in general practice results in better clinical outcomes for people with anxiety and depression.
Peter FM Verhaak, Hilbink-Smolders Mirrian, Verhaak Peter FM, Penninx Brenda WJH, Hilbink-Smolders, Mirrian, Peter Spreeuwenberg, Spreeuwenberg, Peter, Bensing, Jozien M, Brenda WJH Penninx, Verhaak, P.F.M., Hilbink-Smolders, M., {Van Der Meer}, Klaas, Prins, Marijn A, van der Meer, K., Marijn A Prins, Laurant, M.G., Bensing, J.M., van der Meer Klaas, van Marwijk, H.W.J., Verhaak, P.F., van Marwijk Harm WJ, van Marwijk, Harm W. J., Prins, Marijn A., Verhaak, Peter F M, Prins, M.A., Penninx, B.W.J.H., Laurant Miranda GH, Prins Marijn A, Verhaak, Peter F. M., Klaas van der Meer, Marwijk, H.W.J. van, Spreeuwenberg Peter, Harm WJ van Marwijk, Bensing Jozien M, Van Marwijk, Harm, Penninx, Brenda W. J. H., Meer, K. van der, Spreeuwenberg, P., Laurant, Miranda G H, Laurant, Miranda G. H., Miranda GH Laurant, Penninx, Brenda W J H, Laurant, M.G.H., van der Meer, Klaas, Bensing, Jozien M., Jozien M Bensing, Mirrian Hilbink-Smolders   +46 more
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Neural and behavioral markers of inhibitory control predict symptom improvement during internet-delivered cognitive behavioral therapy for depression

Translational Psychiatry
Poor inhibitory control contributes to deficits in emotion regulation, which are often targeted by treatments for major depressive disorder (MDD), including cognitive behavioral therapy (CBT).
Michelle Thai, Elizabeth A. Olson, Stefanie Nickels, Daniel G. Dillon, Christian A. Webb, Boyu Ren, William D. S. Killgore, Scott L. Rauch, Isabelle M. Rosso, Diego A. Pizzagalli   +9 more
doaj   +1 more source