Results 31 to 40 of about 1,107,104 (361)

New Therapeutic Targets for Mood Disorders

The Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate   +8 more
doaj   +1 more source

D-Cycloserine as an augmentation strategy for cognitive behavioral therapy of anxiety disorders. [PDF]

, 2013
The goal of this review is to examine the clinical studies on d-cycloserine, a partial glutamatergic N-methyl-D-aspartate agonist, as an augmentation strategy for exposure procedures during cognitive behavioral therapy for anxiety disorders.
Boettcher, Hannah, Hofmann, Stefan G., Wu, Jade Q.   +2 more
core   +1 more source

Developmental aspects of FXAND in a man with the FMR1 premutation. [PDF]

, 2020
BackgroundFragile X mental retardation 1 (FMR1) premutation can cause developmental problems including autism spectrum disorder (ASD), social anxiety, depression, and attention deficit hyperactivity disorder (ADHD).
Emeka-Nwonovo, Chinelo, Hagerman, Paul, Hagerman, Randi, Santos, Ellery, Schneider, Andrea, Tassone, Flora, Wang, Jun Yi   +6 more
core   +1 more source

Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder

European Journal of Psychotraumatology
Introduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD).
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

Sleep-amount differentially affects fear-processing neural circuitry in pediatric anxiety: A preliminary fMRI investigation. [PDF]

, 2017
Insufficient sleep, as well as the incidence of anxiety disorders, both peak during adolescence. While both conditions present perturbations in fear-processing-related neurocircuitry, it is unknown whether these neurofunctional alterations directly link ...
Carlisi, Christina O, Ernst, Monique, Guyer, Amanda E, Hilbert, Kevin   +3 more
core   +1 more source

Common Dermatoses in Patients with Obsessive Compulsive Disorders [PDF]

, 2015
Obsessive-compulsive disorder is a chronic, debilitating syndrome, consisting of intrusive thoughts- which are experienced as inappropriate by the patient and are producing anxiety- and compulsions, defined as repetitive behaviours produced to reduce ...
Benea, Vasile, Georgescu, Simona Roxana, Matei, Clara, Sarbu, Maria Isabela, Tampa, Mircea   +4 more
core   +3 more sources

Impact of Hoarding and Obsessive–Compulsive Disorder Symptomatology on Quality of Life and Their Interaction With Depression Symptomatology

Frontiers in Psychology, 2022
Hoarding disorder (HD) is a psychiatric condition characterized by difficulty discarding items and accumulation of clutter. Although studies have established the negative impact of HD and compulsive hoarding behavior, fewer have examined the impact on ...
Binh K. Nguyen, Binh K. Nguyen, Jessica J. Zakrzewski, Jessica J. Zakrzewski, Luis Sordo Vieira, Luis Sordo Vieira, Luis Sordo Vieira, Carol A. Mathews, Carol A. Mathews   +8 more
doaj   +1 more source

CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad, Arnau Puig‐Davi, Iñigo Ruíz‐Barrio, Javier Pagonabarraga, Anna Vázquez‐Oliver, Andrea Horta‐Barba, Jaime Kulisevsky, Saül Martínez‐Horta   +7 more
wiley   +1 more source

Trauma-related intrusive memories and anterior hippocampus structural covariance: an ecological momentary assessment study in posttraumatic stress disorder

Translational Psychiatry
Trauma-related intrusive memories (TR-IMs) are hallmark symptoms of posttraumatic stress disorder (PTSD), but their neural correlates remain partly unknown.
Quentin Devignes, Boyu Ren, Kevin J. Clancy, Kristin Howell, Yara Pollmann, Lucia Martinez-Sanchez, Courtney Beard, Poornima Kumar, Isabelle M. Rosso   +8 more
doaj   +1 more source

Mindfulness as an Effective Strategy for Anxiety Relief in Adolescent Patients [PDF]

, 2017
Anxiety disorders affect 6.8 million adults over the age of 18 in the United States, and anxiety disorders are the most common mental health illness in children.
DiBella, Desiree N
core   +1 more source