Results 31 to 40 of about 1,133,566 (357)

Chronic Stress Oppositely Regulates Tonic Inhibition in Thy1-Expressing and Non-expressing Neurons in Amygdala

Frontiers in Neuroscience, 2020
Chronic or prolonged exposure to stress ranks among the most important socioenvironmental factors contributing to the development of neuropsychiatric diseases, a process generally associated with loss of inhibitory tone in amygdala.
Han-Qing Pan, Han-Qing Pan, Wen-Hua Zhang, Wen-Hua Zhang, Cai-Zhi Liao, Cai-Zhi Liao, Ye He, Zhi-Ming Xiao, Xia Qin, Xia Qin, Wei-Zhu Liu, Wei-Zhu Liu, Na Wang, Jia-Xin Zou, Jia-Xin Zou, Xiao-Xuan Liu, Xiao-Xuan Liu, Bing-Xing Pan, Bing-Xing Pan   +18 more
doaj   +1 more source

Psychiatric characterization of children with genetic causes of hyperandrogenism [PDF]

, 2010
Objective: Very little is known about the mental health status in children with genetic causes of hyperandrogenism. This study sought to characterize psychiatric morbidity in this group. Design/methods: Children (8-18 years) with the diagnosis of classic
Ernst, Monique, Green-Golan, Liza, Leschek, Ellen, Merke, Deborah, Müller, Sven, Ng, Pamela, Sinaii, Ninet, VanRyzin, Carol   +7 more
core   +2 more sources

New Therapeutic Targets for Mood Disorders

The Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate   +8 more
doaj   +1 more source

Emergency care provision for, and psychological distress in, survivors of domestic violence

South African Family Practice, 2007
Background: This study aimed (i) to ascertain the number of treatment referrals and information about protection orders given to survivors of domestic violence presenting for emergency trauma care, as reported at the one-month visit, (ii) to obtain a ...
Kate Joyner, Lennette Theunissen, Liezel de Villiers, Sharain Suliman, Timothy Hardcastle, Soraya Seedat   +5 more
doaj   +1 more source

Anger: the unrecognized emotion in emotional disorders [PDF]

, 2016
Anger plays a prominent definitional role in some psychological disorders currently widely scattered across DSM‐5 categories (e.g., intermittent explosive disorder, borderline personality disorder).
Barlow, David H., Cassiello-Robbins, Clair   +1 more
core   +1 more source

Examining hope as a transdiagnostic mechanism of change across anxiety disorders and CBT treatment protocols. [PDF]

, 2020
Hope is a trait that represents the capacity to identify strategies or pathways to achieve goals and the motivation or agency to effectively pursue those pathways.
Barlow, David H., Boswell, James F., D'Souza, Johann, Farchione, Todd J., Gallagher, Matthew W., Long, Laura J., Richardson, Angela   +6 more
core   +1 more source

Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder

European Journal of Psychotraumatology
Introduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD).
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

Self-Regulation of Breathing as a Primary Treatment for Anxiety [PDF]

, 2015
Understanding the autonomic nervous system and homeostatic changes associated with emotions remains a major challenge for neuroscientists and a fundamental prerequisite to treat anxiety, stress, and emotional disorders.
Barnes, Vernon A., Crawford, Molly W., Harden, Kyler, Ravinder, Jerath   +3 more
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Trauma-related intrusive memories and anterior hippocampus structural covariance: an ecological momentary assessment study in posttraumatic stress disorder

Translational Psychiatry
Trauma-related intrusive memories (TR-IMs) are hallmark symptoms of posttraumatic stress disorder (PTSD), but their neural correlates remain partly unknown.
Quentin Devignes, Boyu Ren, Kevin J. Clancy, Kristin Howell, Yara Pollmann, Lucia Martinez-Sanchez, Courtney Beard, Poornima Kumar, Isabelle M. Rosso   +8 more
doaj   +1 more source