Results 101 to 110 of about 71,529 (343)

High‐Performance Oxidation and Nanomolar Detection of Phenylhydrazine Using a 6‐Hydroxyflavone‐Based Molecular Electrocatalyst Functionalized Multiwalled Carbon Nanotube in Batch Injection Analysis

ChemistryOpen, EarlyView.
This study presents a novel, rapid method for in situ functionalization of carbon electrodes using redox‐active form of the 6‐hydroxyflavone. The resulting multiwalled carbon nanotubes with redox‐active HFLA (MWCNT@HFLA‐Redox) electrode enables sensitive, selective detection of toxic phenylhydrazine, with excellent performance (limit of detection: 7 nM)
Valisireddy Lavanya, Kannappan Santhakumar, Annamalai Senthil Kumar   +2 more
wiley   +1 more source

Evaluation of anxiolytic activity of methanolic extract of Urtica urens in a mice model

Behavioral and Brain Functions, 2015
The present study was designed to study anxiolytic property of methanolic extracts of Urtica urens; an important and commonly used for its medicinal properties belongs to urticaceae family.
Z. Doukkali, K. Taghzouti, El Houcine Bouidida, Mohamed Nadjmouddine, Y. Cherrah, K. Alaoui   +5 more
semanticscholar   +1 more source

Reducing General Anesthesia for Lumbar Punctures in Pediatric Patients With Leukemia and Lymphoma, a Quality Improvement Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Curative therapy for most children with leukemia and lymphoma includes multiple lumbar punctures (LPs) for the administration of intrathecal chemotherapy, commonly facilitated with deep sedation or general anesthesia (GA). There is ongoing concern about the potential for neurocognitive deficits induced by GA in the developing brain ...
Karen Arane, Daphne Li, Tara Baxter, Bina Gandhi, Karyn Positano, Melissa Howlett, Tobias Everett, Sarah Alexander   +7 more
wiley   +1 more source

Study of acute toxicity of potential anxiolytic GML-1

Фармакокинетика и Фармакодинамика, 2019
Relevance. Assessment of chronic toxicity is a necessary stage of preclinical research of a newly synthesized pharmacological substance GML-1 having anxiolytic activity.
I. A. Miroshkina, A. V. Sorokina, A. V. Volkova, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov, S. V. Alekseeva, A. D. Durnev   +7 more
doaj   +1 more source

Opioid consumption after lower limb amputation in Medicare beneficiaries

PM&R, EarlyView.
Abstract Background Despite targeted national quality improvement initiatives, opioid prescription and use patterns after lower limb amputation are not well studied. Objective To determine risk factors associated with extended opioid use and rates of high‐risk opioid prescribing after lower limb amputation. Design and setting A retrospective population‐
Alexander N. Khouri, Nishant Ganesh Kumar, Hsou‐Mei Hu, Maryam Yazdanfar, Jennifer F. Waljee, Theodore A. Kung   +5 more
wiley   +1 more source

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT1A and 5-HT7 Antagonists in Animal Models

PLoS ONE, 2015
The aim of this study was to further characterize pharmacological properties of two phenylpiperazine derivatives: 1-{2-[2-(2,6-dimethlphenoxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazynine hydrochloride (HBK-14) and 2-[2-(2-chloro-6-methylphenoxy)ethoxy ...
K. Pytka, A. Partyka, M. Jastrzębska-Więsek, A. Siwek, M. Głuch-Lutwin, Barbara Mordyl, G. Kazek, A. Rapacz, Adrian Olczyk, A. Gałuszka, M. Blachuta, A. Waszkielewicz, H. Marona, J. Sapa, B. Filipek, A. Wesołowska   +15 more
semanticscholar   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos, Martin H. Teicher, Robert M. Post   +2 more
wiley   +1 more source

Managing Acute Behavioural Disturbance in Perinatal Women: A Systematic and State of the Art Review of Guidelines

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Guidelines for managing acute behavioural disturbance typically exclusively focus on care for adults in mental health and related settings, how this should be adapted to safely manage in pregnancy and the early postpartum including in settings such as maternity wards is less clear. Aims To undertake a systematic and state of the art
Megan Galbally, Brendan Jansen, Rebecca Hill, Bo Egan, Josephine Power, Ryan Hodges, Mathew Coleman   +6 more
wiley   +1 more source

Offspring exposure to Crohn's disease during pregnancy and association with milder psychiatric regulatory disturbances in childhood

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Crohn's disease is an inflammatory bowel disorder. Offspring of mothers, with Crohn's disease during pregnancy, had modestly higher risks of the milder regulatory disorders, including early sleeping, continence, and feeding disturbances, but not of other studied neurodevelopmental disorders.
Elin Skott, Gustav Söderberg, MaiBritt Giacobini, Samson Nivins, Xinxia Chen, Daniel Lindqvist, Mika Gissler, Klas Sjöberg, Catharina Lavebratt   +8 more
wiley   +1 more source

Cross‐sectional and longitudinal metabolomics‐based profiles associated with oral contraceptive and progestin‐only pill use: A Finnish population‐based study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In a metabolomics study of over 200 metabolites in 1721 fertile‐aged women, we found that current use of combined oral contraceptives (COC), especially third‐generation and other COCs, is associated with altered levels of several metabolic measures compared to nonuse of hormonal contraception or to use of a levonorgestrel intrauterine device (LNG‐IUD).
Elena Toffol, Jari Haukka, Pekka Jousilahti, Lara Lehtoranta, Anni Joensuu, Timo Partonen, Iris Erlund, Oskari Heikinheimo   +7 more
wiley   +1 more source