Results 231 to 240 of about 71,529 (343)

The Effects of Indirect and Direct Modulation of Endocannabinoid System Function on Anxiety-Related Behavior in Mice Assessed in the Elevated Plus Maze Test. [PDF]

Molecules
Kruk-Slomka M, Dzik A, Biala G.
europepmc   +1 more source

Effects of Oral Macrocyclic Lactone Heartworm Preventatives on Retinal Function and Chromatic Pupillary Light Reflex in Healthy Companion Dogs

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective Determine the effect of oral macrocyclic lactone heartworm‐preventative medications on retinal function and chromatic pupillary light reflex (cPLR) in healthy dogs. Animals Studied Cross‐sectional retrospective: 60 dogs (n = 33 females) with heartworm medication administration status and electroretinogram (ERG) data available ...
Ryan G. Hopper, Allison L. Ludwig, Michele M. Salzman, Ethan Elazegui, Callie M. Rogers, Ellison Bentley, Freya M. Mowat   +6 more
wiley   +1 more source

Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress. [PDF]

Transl Psychiatry
Erkizia-Santamaría I, Horrillo I, Martínez-Álvarez N, Pérez-Martínez D, Rivero G, Erdozain AM, Meana JJ, Ortega JE.   +7 more
europepmc   +1 more source

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

Experimental Physiology, EarlyView.
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto, Anna V. Golubeva, Alvaro Lopez Gallardo, Thomaz F. S. Bastiaanssen, Alexander V. Zhdanov, Gerard M. Moloney, Caitriona Scaife, Jane A. English, Susan A. Joyce, Timothy G. Dinan, John F. Cryan   +10 more
wiley   +1 more source

Anxiolytic Activity of Morellic Acid: Modulation of Diazepam's Anxiolytic Effects, Possibly Through GABAergic Interventions. [PDF]

CNS Neurosci Ther
Bhuia MS, Eity TA, Chowdhury R, Ansari SA, Bappi MH, Nayeem MA, Akter F, Islam MT.   +7 more
europepmc   +1 more source

Exhaustive exercise abolishes REV‐ERB‐α circadian rhythm and shifts the kynurenine pathway to a neurotoxic profile in mice

The Journal of Physiology, EarlyView.
Abstract figure legend Acute exhaustive exercise (EE) reduces REV‐ERB‐α protein levels in skeletal muscle, which impairs its transcriptional repression of kynurenine (KYN) 3‐monooxygenase (KMO), a key enzyme in the KYN pathway that converts KYN into potentially neurotoxic metabolites, collectively referred to as ‘kynurenines’. This study identifies KMO
Alisson Luiz da Rocha, Ana Paula Pinto, Ivo Vieira de Sousa Neto, Vitor Rosetto Muñoz, Bruno Brieda Marafon, Lilian Eslaine Costa Mendes da Silva, José Rodrigo Pauli, Dennys Esper Cintra, Eduardo Rochete Ropelle, Fernando Moreira Simabuco, Leandro Pereira de Moura, Ellen Cristini de Freitas, Donato Americo Rivas, Adelino Sanchez Ramos da Silva   +13 more
wiley   +1 more source

Exploring the Toxicity and Therapeutic Potential of <i>A. dahurica</i> and <i>A. pubescens</i> in Zebrafish Larvae: Insights into Anxiety Treatment Mechanisms. [PDF]

Int J Mol Sci
Herbet M, Widelski J, Ostrowska-Leśko M, Serefko A, Wojtanowski K, Kurek J, Piątkowska-Chmiel I.   +6 more
europepmc   +1 more source

Faculty Opinions recommendation of Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.

, 2002
René Hen
openalex   +1 more source

Treatment Experience Using a Micro‐Induction Buprenorphine Protocol for Chronic Pain in Pediatric Sickle Cell Disease

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Patients with sickle cell disease (SCD) experience painful vaso‐occlusive episodes that increase with age; a subset develops chronic pain (CP). CP is usually managed with acute pain management guidelines despite evidence of ineffectiveness.
Ashwin Patel, Grace Kalmus, Carlton Dampier, Ifeyinwa Osunkwo, Tamara New, Beatrice Gee, Elna Saah   +6 more
wiley   +1 more source

Sex Differences in the Anxiolytic Properties of Common Cannabis Terpenes, Linalool and β-Myrcene, in Mice. [PDF]

NeuroSci
Wagner JK, Gambell E, Gibbons T, Martin TJ, Kaplan JS.   +4 more
europepmc   +1 more source