Results 241 to 250 of about 71,529 (343)

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, Volume 98, Issue 1, Page 35-47, July 2025.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

Anxiolytic, Antidepressant and Healthy Sleep-Promoting Potential of Rosmarinic Acid: Mechanisms and Molecular Targets. [PDF]

Neuropsychiatr Dis Treat
Priya V, Srinivasan D, Priyadarsini S, Dabaghzadeh F, Rana SS, Chengaiyan JG, Sudesh R, Ahmad F.   +7 more
europepmc   +1 more source

Cannabigerol Extraction from a Cannabis Cultivar Using a Supercritical Carbon Dioxide Process

Chemical Engineering &Technology, Volume 48, Issue 7, July 2025.
The aim of this work was to assess for the first time the supercritical fluid extraction (SFE) process feasibility to obtain a CBG‐rich extract from Cannabis. Extraction experiments highlighted that CBG can be properly extracted at 18 MPa and 40 °C and the extraction plant scheme affected CBG recovery and purity.
Lucia Baldino, Alessandra Zanotti, Mariarosa Scognamiglio, Ernesto Reverchon   +3 more
wiley   +1 more source

LACK OF IFENPRODIL ANXIOLYTIC ACTIVITY AFTER ITS MULTIPLE TREATMENT IN CHRONICALLY ETHANOL-TREATED RATS

, 2003
Przemysław Ł. Mikołajczak
openalex   +1 more source

Oxytocin Stimulates Extracellular Ca2+ Influx Through TRPV2 Channels in Hypothalamic Neurons to Exert Its Anxiolytic Effects

Neuropsychopharmacology, 2015
E. V. D. Burg, J. Stindl, Thomas U. Grund, I. Neumann, O. Strauß   +4 more
semanticscholar   +1 more source

Further Structure‐Activity Relationship of G Protein‐Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds

ChemMedChem, Volume 20, Issue 13, July 1, 2025.
Work presented here details the design and characterize novel G protein‐gated inwardly rectifying potassium channels (GIRK)1/2 activators. A new 4,4‐difluorocyclohexylpyrazole have been identified that confers improved potency and selectivity for GIRK1/2 versus GIRK1/4.
Sumaiya Nahid, Fahad Imtiaz Rahman, Yu Du, Brittany D. Spitznagel, Sandeep K. Singh, Yashpal S. Chhonker, Daryl J. Murry, C. David Weaver, Corey R. Hopkins   +8 more
wiley   +1 more source

Comparing the Costs Associated with Anxiolytic Agents for Reducing Distress in Children Undergoing Laceration Repair in the Emergency Department. [PDF]

J Am Coll Emerg Physicians Open
Tran NA, Lin YS, Pechlivanoglou P, Ali S, Coyle D, Poonai N, Heath A.   +6 more
europepmc   +1 more source

Effect of Anxiolytic Drugs on Air-Puff-Elicited Ultrasonic Vocalization in Adult Rats

, 2003
Hiroyuki Naito, Amane Nakamura, Maki Inoue, Yoshihiko Suzuki   +3 more
openalex   +2 more sources

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, Volume 17, Issue 7, Page 1118-1130, July 2025.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression. [PDF]

Front Pharmacol
Li Z, Wan L, Dong J, Li J, Liu J.
europepmc   +1 more source