Results 31 to 40 of about 53,857 (331)

Choline preparations in the treatment of asthenic states: modernity and perspectives (A Clinical Case Presentation)

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2022
In this article, we want to present the reader with an interesting clinical case from authors’ practice, which, in our opinion, clearly demonstrates the efficacy and safety of using Gliatilin (choline alfoscerate) as a part of combination therapy in a 19-
Yu. V. Bykov, R. A. Bekker
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THE INFLUENCE OF 2-OXOINDOLINE-3-GLYOXYLIC ACID DERIVATIVES ON THE NEUROPHYSIOLOGICAL REACTIONS OF RATS IN THE “BLACK AND WHITE CHAMBER” TEST

Проблеми екології та медицини, 2023
The number of patients with an anxiety pathology is constantly growing, which requires the search and development of new remedies for protection. The aim of this research is to establish the presence of anxiolytic activity in derivatives of 2-oxoindolin ...
O.M. Bilovol, R.V. Lutsenko, I.I. Knyazkova, S.V. Kolisnyk, E.G. Shakina   +4 more
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THE EFFICACY OF ANTIHYPERTENSIVE TREATMENT COMBINATION WITH ANXIOLYTICS IN HYPERTENSIVES WITH ANXIETY DISORDER

Российский кардиологический журнал, 2017
Aim. To compare the influence of the simple and combined with anxiolytic drug tofisopam (AT) antihypertesion therapy (AHT) on the 24-hour blood pressure (BP) profile, anxiety level and life quality of patients with uncontrolled arterial hypertension and ...
D. V. Kovalev, V. V. Skibitsky, A. N. Kurzanov, A. I. Ponomareva   +3 more
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β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice

Cell Reports Medicine, 2021
Summary: Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage.
Nicolas Panayotis, Philip A. Freund, Letizia Marvaldi, Tali Shalit, Alexander Brandis, Tevie Mehlman, Michael M. Tsoory, Mike Fainzilber   +7 more
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Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond

Neurobiology of Stress, 2019
The recent FDA approval of the neurosteroid, brexanolone (allopregnanolone), as a treatment for women with postpartum depression, and successful trials of a related neuroactive steroid, SGE-217, for men and women with major depressive disorder offer the ...
C. Zorumski, S. Paul, D. Covey, S. Mennerick   +3 more
semanticscholar   +1 more source

Therapy as an art: how to cope with patient anxiety

Лечащий Врач, 2021
From 17 to 20 February 2021, the XVII interdisciplinary conference with international participation «Wein's Readings» was held online in Moscow. On February 18, as part of this event, with the support of Materia Medica, a symposium entitled «Therapy as ...
I. V. Kovaleva, N. D. Fomenko
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New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Considering the allosteric regulation of mGlu receptors for potential therapeutic applications, we developed a group of 1,2,4-oxadiazole derivatives that displayed mGlu4 receptor positive allosteric modulatory activity (EC50 = 282–656 nM).
Anna Stankiewicz, Katarzyna Kaczorowska, Ryszard Bugno, Aneta Kozioł, Maria H. Paluchowska, Grzegorz Burnat, Barbara Chruścicka, Paulina Chorobik, Piotr Brański, Joanna M. Wierońska, Beata Duszyńska, Andrzej Pilc, Andrzej J. Bojarski   +12 more
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Use of antidepressants and anxiolytics in early pregnancy and the risk of preeclampsia and gestational hypertension: a prospective study

BMC Pregnancy and Childbirth, 2019
BackgroundWe investigated the association between antidepressant and anxiolytic exposure during the first and early second trimester of pregnancy (
N. Bernard, J. Forest, George M. Tarabulsy, E. Bujold, D. Bouvier, Y. Giguère   +5 more
semanticscholar   +1 more source

Anxiolytics targeting GABAA receptors: Insights on etifoxine

World Journal of Biological Psychiatry, 2018
Objectives: Anxiety and adjustment disorders are among the most prevalent mental health conditions. This review focuses on γ-aminobutyric acid receptor type A (GABAAR)-mediated anxiolysis, describing the action of both endogenous and exogenous modulators
P. Poisbeau, G. Gazzo, L. Calvel
semanticscholar   +1 more source

Benzodiazepine and Z-Drug Use in Switzerland: Prevalence, Prescription Patterns and Association with Adverse Healthcare Outcomes

Neuropsychiatric Disease and Treatment, 2021
Salome Landolt,1 Thomas Rosemann,1 Eva Blozik,1,2 Beat Brüngger,2 Carola A Huber1,2 1Institute of Primary Care, University of Zürich, University Hospital Zürich, Zürich, Switzerland; 2Department of Health Sciences, Helsana Insurance ...
Landolt S, Rosemann T, Blozik E, Brüngger B, Huber CA   +4 more
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