Results 51 to 60 of about 23,910 (287)

New users of anxiolytics and sedatives in Sweden—Drug type, doses, prescribers' characteristics, and psychiatric comorbidity in more than 750,000 patients

International Journal of Methods in Psychiatric Research
Objectives Anxiety and sleep disorders are common in the population and anxiolytics and sedatives are widely used. Our aim was to describe the drug utilization of new users of anxiolytics and sedatives in adults including type of drug, doses, prescribers'
Elin Dahlén, Carola Bardage, Paulina Tuvendal, Rickard Ljung   +3 more
doaj   +1 more source

Anxiolytics, sedatives and hypnotics [PDF]

, 2022
Anxiolytics and sedatives are used in current anaesthetic practice for two main reasons: for anxiolysis before surgery and as adjuvants during anaesthesia. A wide choice of agents are available.
Anthony Absalom, Beune, Thimpe, Thimpe Beune, Absalom, Anthony; id_orcid, Absalom, Anthony   +4 more
core   +2 more sources

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Современные проблемы клинических исследований новых анксиолитиков и антидепрессантов

Современная терапия психических расстройств, 2020
Введение: Качество и результаты клинических исследований в современной психиатрии имеют важное значение, поскольку они служат основой для клинических рекомендаций. Однако многие аспекты проведения исследований антидепрессантов и анксиолитиков в последнее
Сюняков, Т.С., Незнамов, Г.Г.   +1 more
doaj   +1 more source

Clinical pharmacology of anxiolytics

, 2018
It is increasingly diffi cult to defi ne what an anxiolytic is, since anxiety is multiple although many symptoms are common. On the other hand the most used drugs in different forms of anxiety were fi rst used as antidepressants.
Michel Bourin, Bourin Michel
core   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source

Effects of Cannabidiol‐Rich Cannabis Oil on Facial Expression Recognition and Theory of Mind in Children With Autism Spectrum Disorder: A Randomized Clinical Trial

Autism Research, EarlyView.
ABSTRACT To evaluate, in a post hoc subanalysis, the effects of cannabidiol (CBD)‐rich cannabis oil on facial expression recognition and theory of mind in children with autism spectrum disorder (ASD). This post hoc subanalysis included children from a double‐blind, randomized, placebo‐controlled trial who completed social cognition assessments at ...
Wandersonia Moreira Brito Medeiros, Estácio Amaro da Silva Junior, Katy Lísias Gondim Dias de Albuquerque, Marine Diniz da Rosa, Amanda Gleiciane de Lima Oliveira, Maycon Jônatas da Silva, João Vitor Andrade Fernandes, Emily Caroline Costa Vieira, João Paulo Mendes dos Santos, Thais Cavalcanti Borges, Ana Hermínia Andrade e Silva, Carlos Espínola Neto Segundo, Nelson Torro‐Alves   +12 more
wiley   +1 more source

Chronic pain and depression in patients with rheumatoid arthritis: results of five - year follow - up [PDF]

Терапевтический архив, 2019
The aim of the study was to analyze the factors affecting chronic pain in patients with rheumatoid arthritis (RA). Materials and methods. 128 patients with reliable diagnosis of RA [111 (86.7%) women and 17 (13.3%) men] were examined.
T A Lisitsyna, A A Abramkin, D Yu Veltishchev, O F Seravina, O B Kovalevskaya, A E Zeltyn, S I Glukhova, E L Nasonov, V N Krasnov   +8 more
doaj   +1 more source

Determinants of Coprescription of Anxiolytics with Antidepressants in General Practice

, 2007
International audienceOBJECTIVES: Anxiolytics are the most frequently prescribed psychotropic drugs in France. General practitioners (GPs) tend to prescribe anxiolytics and other benzodiazepines to patients with major depressive disorders (MDD). However,
Pierre Verger, Saliba, B, Anne Lovell, Verger, P, Gilles Bouvenot, Kovess-Masféty, V, Bouvenot, G, Bérengère Saliba, Villani, P, Lovell, Anne M, Rouillon, F, Frédéric Rouillon, Patrick Villani, Viviane Kovess-Masféty   +13 more
core   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source