Results 51 to 60 of about 53,857 (331)

An update on the pharmacological treatment of anxiety and related disorders

South African Family Practice, 2016
The anxiety disorders, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are common and debilitating, often coexist with medical and psychiatric conditions, and usually require long-term treatment.
K. Outhoff
doaj   +1 more source

Современные проблемы клинических исследований новых анксиолитиков и антидепрессантов

Современная терапия психических расстройств, 2020
Введение: Качество и результаты клинических исследований в современной психиатрии имеют важное значение, поскольку они служат основой для клинических рекомендаций. Однако многие аспекты проведения исследований антидепрессантов и анксиолитиков в последнее
Сюняков, Т.С., Незнамов, Г.Г.   +1 more
doaj   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Phenylpropanoids as a class of natural biologically active organo-protective compounds

Фармация и фармакология (Пятигорск)
The aim of the work was to analyze the current research state of phenylpropanoids as a special specific class of biologically active compounds and the prospects for their use for the development of medicines and biologically active food additives ...
V. A. Kurkin, N. R. Varina, E. V. Avdeeva, I. V. Ruzaeva   +3 more
doaj   +1 more source

Clinical pharmacology of anxiolytics

, 2018
It is increasingly diffi cult to defi ne what an anxiolytic is, since anxiety is multiple although many symptoms are common. On the other hand the most used drugs in different forms of anxiety were fi rst used as antidepressants.
Michel Bourin, Bourin Michel
core   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Determinants of Coprescription of Anxiolytics with Antidepressants in General Practice

, 2007
International audienceOBJECTIVES: Anxiolytics are the most frequently prescribed psychotropic drugs in France. General practitioners (GPs) tend to prescribe anxiolytics and other benzodiazepines to patients with major depressive disorders (MDD). However,
Pierre Verger, Saliba, B, Anne Lovell, Verger, P, Gilles Bouvenot, Kovess-Masféty, V, Bouvenot, G, Bérengère Saliba, Villani, P, Lovell, Anne M, Rouillon, F, Frédéric Rouillon, Patrick Villani, Viviane Kovess-Masféty   +13 more
core   +1 more source

Chronic pain and depression in patients with rheumatoid arthritis: results of five - year follow - up [PDF]

Терапевтический архив, 2019
The aim of the study was to analyze the factors affecting chronic pain in patients with rheumatoid arthritis (RA). Materials and methods. 128 patients with reliable diagnosis of RA [111 (86.7%) women and 17 (13.3%) men] were examined.
T A Lisitsyna, A A Abramkin, D Yu Veltishchev, O F Seravina, O B Kovalevskaya, A E Zeltyn, S I Glukhova, E L Nasonov, V N Krasnov   +8 more
doaj   +1 more source

Help‐Seeking and Substance Use Among Police Staff After the 2018 Strasbourg Christmas Market Attack

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background The use of mental health services by police staff is usually low. After the 2018 attack on the Strasbourg Christmas market, police officers exposed to psychotraumatic risks were found to have a higher PTSD risk. This study aims to describe the help‐seeking and substance use by police staff after the attack.
Nathalie Nourry, Ludivine Nohales, Laurence Lalanne, Emmanuel Fort, Maria Gonzalez, Pierre Vidailhet, Amaury C. Mengin, Barbara Charbotel   +7 more
wiley   +1 more source

The Association Between the Use of Anxiolytics and the Quality of Life in Elderly People

, 2023
Uvod: Anksiolitici su skupina lijekova koji se koriste u liječenju anksioznosti poremećaja. Dugotrajna upotreba ovih lijekova može imati negativan utjecaj na kvalitetu života, osobito kod starijih osoba. Cilj: Procijeniti povezanost uporabe anksiolitika
Konječić, Ana
core   +1 more source