Results 61 to 70 of about 53,857 (331)

Prototypical anxiolytics do not reduce anxiety-like behavior in the open field in C57BL/6J mice

open access: yesPharmacology, Biochemistry and Behavior, 2015
Understanding and effectively treating anxiety disorders are a challenge for both scientists and clinicians. Despite a variety of available therapies, the efficacy of current treatments is still not optimal and adverse side effects can result in non ...
T. Thompson   +2 more
semanticscholar   +1 more source

Use of anxiolytics and hypnotics - a pilot study

open access: yes, 2007
Introduction: Benzodiazepine anxiolytics and hypnotics are often used in therapy. Aim: To study the use of anxiolytics and hypnotics among pharmacy clients in the town of Plovdiv.Materials and methods: In 2005 a questionnaire study was carried out on the
Krasteva, E.; Medical University of Plovdiv   +2 more
core   +1 more source

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee   +3 more
wiley   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Antidepressants, anxiolytics, and hypnotics in pregnancy and lactation

open access: yesIndian Journal of Psychiatry, 2015
Aims: Untreated perinatal depression and anxiety disorders are known to have significant negative impact on both maternal and fetal health. Dilemmas still remain regarding the use and safety of psychotropics in pregnant and lactating women suffering from
D. Ram, S. Gandotra
semanticscholar   +1 more source

Psychiatric outcomes 10 years after treatment with antidepressants or anxiolytics

open access: yes, 2008
Antidepressants and anxiolytics have demonstrated short-term efficacy; however, little is known about the long-term effectiveness of these ...
Colman, Ian   +9 more
core   +1 more source

Quality indicators for safe and effective medication use in long‐term care facilities: A modified Delphi study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This modified Delphi study aimed to achieve expert agreement on quality indicators (QIs) suitable for application at the population level, to evaluate quality use of medications and pharmacist services in long‐term care facilities (LTCFs). Methods We conducted a two‐round modified online Delphi study with a multidisciplinary panel of Australian ...
Daria S. Gutteridge   +10 more
wiley   +1 more source

The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis

open access: yesBrazilian Journal of Medical and Biological Research, 2001
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether ...
R. Andreatini   +13 more
doaj   +1 more source

Medical and Nonmedical Use of Prescription Benzodiazepine Anxiolytics among U.S. High School Seniors

open access: yesAddictive Behaviours, 2014
Objectives To examine the lifetime prevalence of medical and nonmedical use of prescription benzodiazepine anxiolytics among U.S. high school seniors and to assess substance use behaviors based on lifetime histories of medical and nonmedical use of ...
S. McCabe, Brady T. West
semanticscholar   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory   +13 more
wiley   +1 more source

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