Results 91 to 100 of about 2,570 (163)

Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning

The Journal of Clinical Hypertension, Volume 27, Issue 1, January 2025.
ABSTRACT Preeclampsia (PE) is a pregnancy‐specific disorder characterized by an unclearly understood pathogenesis and poses a great threat to maternal and fetal safety. Cuproptosis, a novel form of cellular death, has been implicated in the advancement of various diseases. However, the role of cuproptosis and immune‐related genes in PE is unclear.
Tiantian Yu, Guiying Wang, Xia Xu, Jianying Yan   +3 more
wiley   +1 more source

Abutilon indicum (L.) Sweet Extracts Inhibit Key Glucose Metabolic Enzymes While Enhancing Glucose Transport in L6 Myotubes and 3T3L1 Adipocytes

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Background: Abutilon indicum (L.) Sweet (Malvaceae) is a traditional medicinal plant known for its antidiabetic properties in Ayurveda and other health systems. Aims: This study aims to profile metabolites in Abutilon indicum (L.) Sweet extracts (AI) and elucidate their antidiabetic mechanisms through bioinformatics and experimental methods.
Subhadip Banerjee, Pravaree Phuneerub, Wuttichai Jaidee, Narawadee Rujanapun, Thidarat Duangyod, Kulwadee Malee, Wisanu Maneerat, Virayu Suthiphasilp, Surat Laphookhieo, Salfarina Ramli, Siau Hui Mah, Kitthisak Khlaeo Chansukh, Poonsit Hiransai, Panupong Puttarak, Satyajit D. Sarker, Lutfun Nahar, Rawiwan Charoensup, Mohamed Afifi   +17 more
wiley   +1 more source

Hepatic inflammation facilitates transcription-associated mutagenesis via AID activity and enhances liver tumorigenesis. [PDF]

, 2015
First published online: May 12, 2015Chronic inflammation triggers the aberrant expression of a DNA mutator enzyme, activation-induced cytidine deaminase (AID), and contributes to tumorigenesis through the accumulation of genetic aberrations.
Chiba, Tsutomu, Eso, Yuji, Ikeda, Atsuyuki, Marusawa, Hiroyuki, Matsumoto, Tomonori, Matsumoto, Yuko, Nishijima, Norihiro, Shimizu, Takahiro   +7 more
core   +1 more source

Triple junctions and low angle boundaries [PDF]

, 2006
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2006.Includes bibliographical references (leaf 21).Certain properties, such as cracking or corrosion, can occur mainly along grain boundaries. Certain types
Rodrigues, Vinay
core  

Dopamine replacement therapy modulates DDC, prolactin and AOC3 levels in Parkinson’s disease

Abstract Dopa decarboxylase (DDC) is a candidate biomarker in Parkinson’s disease (PD), but its levels are influenced by dopamine replacement therapy (DRT), complicating interpretation. We used high-throughput proteomics to analyze serum and CSF samples from PD patients, individuals with idiopathic REM-sleep behaviour disorder, and controls to ...
Ludo Hillegondsberg, Shahzad Ahmad, Tanja Zerenner, Michael Lawton, Karolien Groenewald, Micah Fletcher, Yoav Ben-Shlomo, Richard Wade-Martins, Avigail Taylor, Alexander Thompson, Michele Hu   +10 more
openaire   +1 more source

Suspension Culture Optimization and Transcriptome-Guided Identification of Candidate Regulators for Militarine Biosynthesis in Bletilla striata

Horticulturae
Background: Bletilla striata is a medicinal orchid, whose bioactive constituent militarine has therapeutic interest but limited natural availability.
Yang Li, Mengwei Xu, Hongwei Li, Ning Yang, Weie Wen, Lin Li, Laoxeun Yising, Sysouvong Vadsana, Vannavong Sonekeo, Delin Xu   +9 more
doaj   +1 more source

Unveils key proteins in Xinjiang goat muscle linked to post-mortem meat quality: A TMT-based proteomic analysis

Food Chemistry: X
An extensive proteomic analysis utilizing the tandem mass tag (TMT) method was conducted to investigate the changes in protein expression in the longissimus dorsi muscle of Xinjiang goats over various post-mortem intervals: immediately after death within
Duoduo Zhang, Hong Yu, Minghui Gu, Shiquan Zhang, Xiaolin Ma, Wei Zhang, Yanlei Zhu, Majida Al-Wraikat, Mohamed Aamer Abubaker, Rui Zhang, Yongfeng Liu   +10 more
doaj   +1 more source

Discovering Genes Involved in the Synthesis of Secondary Metabolites From the Seeds of Moringa Oleifera Through Transcriptome Analysis [PDF]

, 2021
Moringa oleifera is a widely used crop that produces seeds with a plethora of benefits encompassing health and nutrition. Secondary metabolite compounds were determined in the seeds of Moringa oleifera that possess nutritional and pharmacological ...
Discar, Ma. Divina Kristi A, Panes, Vivian A   +1 more
core   +1 more source

Exome-wide association study of pancreatic cancer risk [PDF]

, 2018
We conducted a case-control exome-wide association study to discover germline variants in coding regions that affect risk for pancreatic cancer, combining data from 5 studies. We analyzed exome and genome sequencing data from 437 patients with pancreatic
Biankin, Andrew, Borgida, Ayelet, Cleary, Sean, Connor, Ashton A., Cook, Natalie, Denroche, Robert E., Gallinger, Steven, Grant, Robert C., Grimmond, Sean M., Klein, Alison P., Lemire, Mathieu, Moore, Malcolm, Peterson, Gloria, Roberts, Nicholas J., Smith, Alyssa L., Stein, Lincoln, Virtanen, Carl, Wilson, Julie M., Zogopolous, George   +18 more
core   +1 more source

Plasma enhances AOC3 activity from Zinc-α2-glycoprotein is an inhibitor of amine oxidase copper-containing 3

, 2019
Supplemental Fig. 1 A, B and C, [14C]-benzylamine assay: Different volumes of murine wt, AOC3 k.o. and ZAG k.o. plasma were tested for amine oxidase activity. In parallel, the same volumes were tested in the presence of the highly selective AOC3 inhibitor LJP1586.
openaire   +1 more source