Results 71 to 80 of about 2,570 (163)

How Do Cancer Cells Create Cancer‐Associated Fibroblast Subtypes? Impacts of Extracellular Vesicles on Stromal Diversity

Cancer Science, Volume 116, Issue 9, Page 2347-2361, September 2025.
Cancer‐associated fibroblasts (CAFs) are the major component of the tumor stroma. This review will highlight the CAF subtypes within the tumor microenvironment and their role in tumor progression. CAF subtype induction by extracellular vesicles (EVs) and their significance, which we reported previously, are also discussed.
Yutaka Naito
wiley   +1 more source

β‐Sitosterol as an Anti‐Tumour Active Component of Herba Sarcandrae Inhibits Colorectal Cancer Progression Through Up‐Regulation of TBX20

Journal of Cellular and Molecular Medicine, Volume 29, Issue 17, September 2025.
ABSTRACT Colorectal cancer (CRC) is a common malignant tumor of the digestive tract with a high incidence rate. Herba Sarcandrae (HS) is an antipyretic and has been reported to have anti‐cancer effects. This study explored the impacts of β‐sitosterol on the sensitivity of CRC to 5‐fluorouracil (5‐FU) and oxaliplatin and the stability of TBX20 protein ...
Haixiao Yuan, Weiqing Feng, Shaohua Yang, Hao Yin, Shaoyong Ouyang, Hong Xie, Hongmei Tang, Xiaowei Ou, Xianling Gong, Jie Yuan   +9 more
wiley   +1 more source

Analgesic and Anti-Inflammatory Effects of the Novel Semicarbazide-Sensitive Amine-Oxidase Inhibitor SzV-1287 in Chronic Arhtritis Models of the Mouse [PDF]

, 2017
L
Bogdán, Dóra, Borbély, Éva, Botz, Bálint, Csepregi, Janka Zsófia, Helyes, Zsuzsanna, Horváth, Ádám, Juhász, Tamás, Keeble, Julie, Kemény, Ágnes, Menghis, Awt, Mátyus, Péter, Mócsai, Attila, Pintér, Erika, Tékus, Valéria, Zákány, Róza   +14 more
core   +5 more sources

Potential New Expression Biomarkers for Anorexia Nervosa

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 4, June 2025.
ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi, Nicolas Lebrun, Justine Vily Petit, Odile Viltart, Philibert Duriez, Benjamin Saint‐Pierre, Philip Gorwood, Nicolas Ramoz, Thierry Bienvenu   +8 more
wiley   +1 more source

Correlation of histopathologic characteristics to protein expression and function in malignant melanoma. [PDF]

PLoS ONE, 2017
Metastatic melanoma is still one of the most prevalent skin cancers, which upon progression has neither a prognostic marker nor a specific and lasting treatment. Proteomic analysis is a versatile approach with high throughput data and results that can be
Charlotte Welinder, Krzysztof Pawłowski, A Marcell Szasz, Maria Yakovleva, Yutaka Sugihara, Johan Malm, Göran Jönsson, Christian Ingvar, Lotta Lundgren, Bo Baldetorp, Håkan Olsson, Melinda Rezeli, Thomas Laurell, Elisabet Wieslander, György Marko-Varga   +14 more
doaj   +1 more source

Gene profiling suggests a common evolution of bladder cancer subtypes [PDF]

, 2013
Background Bladder cancer exists as several distinct subtypes, including urothelial carcinoma (UCa), squamous cell carcinoma (SCCa), adenocarcinoma and small cell carcinoma. These entities, despite showing distinct morphology and clinical behavior, arise
Bin T Teh, David Petillo, Donna E Hansel, Zhongfa Zhang   +3 more
core   +2 more sources

Management of metabolic dysfunction–associated steatotic liver disease (MASLD)—An expert consensus statement from Indian diabetologists' perspective

Diabetes, Obesity and Metabolism, Volume 27, Issue S4, Page 3-20, June 2025.
Abstract In India, the increasing prevalence of diabetes and obesity poses a significant threat towards a surge in the incidence of metabolic dysfunction‐associated steatotic liver disease (MASLD), formerly known as non‐alcoholic fatty liver disease (NAFLD).
Abdul Hamid Zargar, Anil Bhansali, Anirban Majumdar, Anuj Maheshwari, Arpandev Bhattacharyya, Arundhati Dasgupta, Banshi Damodarlal Saboo, Bipin Kumar Sethi, Debmalya Sanyal, Krishna G. Seshadri, Neeta Rohit Deshpande, Nitin Kapoor, Om Jitendra Lakhani, Pradeep Gopal Talwalkar, Pramila Kalra, Rabindera Nath Mehrotra, Rakesh Kumar Sahay, Rishi Shukla, Saket Kant, Sambit Das, Sanjay Chunilal Agarwal, Sanjeev Ratnakar Phatak, Shanmugasundar G., Shashank Rameshchandra Joshi, Shehla Sajid Shaikh, Sosale Ramachandra Aravind, Soumik Goswami, Sujoy Ghosh, Vijay Kumar Panikar, Viswanathan Mohan   +29 more
wiley   +1 more source

Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study [PDF]

, 2014
Colorectal adenomas are cancer precursor lesions of the large bowel. A multitude of genomic and epigenomic changes have been documented in these preinvasive lesions, but their impact on the protein effectors of biological function has not been ...
Barkow-Oesterreicher, Simon, Buffoli, Federico, Grossmann, Jonas, Laczko, Endre, Marra, Giancarlo, Nanni, Paolo, Shay, Jerry W, Staiano, Teresa, Tiwari, Amit, Uzozie, Anuli   +9 more
core   +1 more source

The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome

PROTEOMICS, Volume 25, Issue 7, April 2025.
ABSTRACT Cell surface proteins (surfaceome) represent key signalling and interaction molecules for therapeutic targeting, biomarker profiling and cellular phenotyping in physiological and pathological states. Here, we employed coronary artery perfusion with membrane‐impermeant biotin to label and capture the surface‐accessible proteome in the neo ...
Iasmin Inocencio, Alin Rai, Daniel Donner, David W. Greening   +3 more
wiley   +1 more source

Herbivore defense responses and associated herbivore defense mechanism as revealed by comparing a resistant wild soybean with a susceptible cultivar

Crop Journal, 2015
Plants have evolved sophisticated defense mechanisms against herbivores to help them adapt to the environment. Understanding the defense mechanisms in plants can help us control insects in a more effective manner.
Xiaoyi Wang , Haifeng Chen , Zhihui Shan , Qingnan Hao , Chanjuan Zhang , Zhonglu Yang , Xiaojuan Zhang , Songli Yuan , Dezhen Qiu, Shuilian Chen , Yongqin Jiao , Xin'an Zhou   +11 more
doaj   +1 more source