Results 51 to 60 of about 2,570 (163)

Dietary Supplementation with Boswellia serrata, Verbascum thapsus, and Curcuma longa in Show Jumping Horses: Effects on Serum Proteome, Antioxidant Status, and Anti-Inflammatory Gene Expression [PDF]

, 2023
: Intense exercise can cause inflammation and oxidative stress due to the production of reactive oxygen species. These pathophysiological processes are interdependent, and each one can induce the other, creating a vicious circle.
Angeloni, Cristina, Beghelli, Daniela, Bistoni, Onelia, Catalano, Chiara, Cavallucci, Clarita, Giusti, Laura, Hrelia, Silvana, Lucacchini, Antonio, Mazzoni, Maria Rosa, Nuccitelli, Anna, Ronci, Maurizio, Zallocco, Lorenzo   +11 more
core   +4 more sources

Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes [PDF]

, 2012
Genetic variation in the expression of human XMETs leads to inter-individual variability in metabolism of therapeutic agents as well as differed susceptibility to various diseases.
David A Flockhart, Fan eYang, Lang eLi, Naga eChalasani, Rongrong eWei, Thomas J. Urban, Wanqing eLiu, Wanqing eLiu   +7 more
core   +2 more sources

Do ridge-ridge-fault triple junctions exist on Earth? Evidence from the Aden-Owen-Carlsberg junction in the NW Indian Ocean

, 2008
International audienceThe triple junctions predicted to be ridge^ridge^fault (RRF) types on the basis of large- scale plate motions are theAzores triple junction between theGloria Fault and theMid-AtlanticRidge, the Juan Fernandez triple junction between
Argus, Barton, Bellahsen, Bird, Bird, Briais, Bunce, Cann, Cannat, Chamot-Rooke, Chaubey, Cochran, Cochran, Cochran, Cochran, d'Acremont, d'Acremont, Delescluse, DeMets, DeMets, DeMets, Dyment, Dziewonski, Edwards, Einarsson, Ellouz-Zimmermann, Engdahl, Falconer, Fernandes, Fournier, Fournier, Fournier, Fournier, Fournier, Gaedicke, Gaedicke, Gordon, Gunnell, Hey, Honsho, Huchon, Ildefonse, Jestin, Klein, Kleinrock, Kreemer, Kruse, Lafoy, Larson, Lastras, Laughton, Lepvrier, Leroy, Ligi, Ligi, Lonsdale, Luis, Macdonald, Matthews, Matthews, McKenzie, McKenzie, Mercuriev, Merkouriev, Minshull, Mitchell, Mitchell, Mitchell, Mitchell, Mountain, Munschy, Nocquet, Norton, Ohara, Patriat, Patriat, Peters, Petit, Quittmeyer, Reilinger, Royer, Schmidt, Sclater, Searle, Searle, Sella, Shillington, Smewing, Spencer, Srivastava, Stein, Sykes, Sykes, Talling, Tapscott, Tiberi, Tucholke, van Wijk, Vigny, Vogt, Wessel, Whitmarsh, Wilson   +102 more
core   +4 more sources

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization [PDF]

, 2016
Regenerative medicine is a novel approach for treating conditions in which enhanced bone regeneration is required. We identified transgelin (TAGLN), a transforming growth factor beta (TGFβ)-inducible gene, as an upregulated gene during in vitro ...
Alajez, N. M., Aldahmash, A., Alfayez, M., Dawud, R. A., Elsafadi, M., Hamam, R., Kassem, M., Mahmood, A., Manikandan, M.   +8 more
core   +2 more sources

Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury [PDF]

, 2012
International audienceWe have analyzed transcriptomic, proteomic and metabolomic profiles of hepatoma cells cultivated inside a microfluidic biochip with or without acetaminophen (APAP). Without APAP, the results show an adaptive cellular response to the
Aninat, Caroline, Bois, Frédéric Y., Brochot, Céline, Bunescu, Andrei, Corlu, Anne, Dumas, Marc-Emmanuel, Elena-Herrmann, Bénédicte, Griscom, Laurent, Leclerc, Eric, Legallais, Cécile, Prot, Jean-Matthieu, Razan, Florence, Snouber, Leila Choucha   +12 more
core   +4 more sources

Transcriptomic and Metabolomic Analyses Reveal Key Metabolites, Pathways and Candidate Genes in Sophora davidii (Franch.) Skeels Seedlings Under Drought Stress

Frontiers in Plant Science, 2022
Soil aridification and desertification are particularly prominent in China’s karst areas, severely limiting crop yields and vegetation restoration. Therefore, it is very important to identify naturally drought-tolerant plant species.
Xin Zhao, Li-Juan Huang, Xiao-Fu Sun, Li-Li Zhao, Pu-Chang Wang   +4 more
doaj   +1 more source

Cdkn2a deficiency promotes adipose tissue browning. [PDF]

, 2018
Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk.
Annicotte, J.S., Bonnefond, A., Carney, C., Caron, E., Dani, C., Durand, E., Fajas, L., Froguel, P., Gromada, X., Hannou, S.A., Lopez-Mejia, I.C., Oger, F., Rabearivelo, I., Rabhi, N., Salas, E., Yao, X.   +15 more
core   +3 more sources

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
N6‐methyladenosine RNA methylation regulators are intricately linked with the development of polycystic ovary syndrome (PCOS) and may influence immune cell infiltration in affected individuals. This study enhances our understanding of the molecular interactions in PCOS and suggests potential biomarkers for diagnosis and targets for therapeutic ...
Wenting Xu, Lingli Shi, Aifang Lu, Lijuan Cui, Haiqing Qian, Jiahui Wang, Mengyu Tang, Lili Zhu, Lihong Wang   +8 more
wiley   +1 more source