Results 31 to 40 of about 2,570 (163)

Identification of Stage-Specific Breast Markers using Quantitative Proteomics [PDF]

open access: yes, 2013
YesMatched healthy and diseased tissues from breast cancer patients were analyzed by quantitative proteomics. By comparing proteomic profiles of fibroadenoma (benign tumors, three patients), DCIS (noninvasive cancer, three patients), and invasive ductal ...
Alexander H.   +69 more
core   +1 more source

Detecting the Hormonal Pathways in Oilseed Rape behind Induced Systemic Resistance by Trichoderma harzianum TH12 to Sclerotinia sclerotiorum. [PDF]

open access: yesPLoS ONE, 2017
Plants have the ability to resist pathogen attack after infection or treatment with biotic and abiotic elicitors. In oilseed rape plant Brassica napus AACC and in the artificially synthesized Raphanus alboglabra RRCC, the root-colonizing Trichoderma ...
Jawadayn Talib Alkooranee   +7 more
doaj   +1 more source

Cross-talk between signaling pathways leading to defense against pathogens and insects [PDF]

open access: yes, 2008
In nature, plants interact with a wide range of organisms, some of which are harmful (e.g. pathogens, herbivorous insects), while others are beneficial (e.g.
de Vos, M.   +13 more
core   +8 more sources

Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes. [PDF]

open access: yesPLoS Biology, 2018
Copper (Cu) has emerged as an important modifier of body lipid metabolism. However, how Cu contributes to the physiology of fat cells remains largely unknown.
Haojun Yang   +9 more
doaj   +1 more source

Transcriptome and Metabolome Analyses of Codonopsis convolvulacea Kurz Tuber, Stem, and Leaf Reveal the Presence of Important Metabolites and Key Pathways Controlling Their Biosynthesis

open access: yesFrontiers in Genetics, 2022
Codonopsisconvolvulacea Kurz. var. vinciflora (Kom.) L.T. Shen is a member of Campanulaceae, which is used in traditional Chinese medicine. However, apart from a few Codonopsis species, no detailed knowledge is available on the metabolite composition and
Fang Yuan   +3 more
doaj   +1 more source

Gene-expression profiling of microdissected breast cancer microvasculature identifies distinct tumor vascular subtypes [PDF]

open access: yes, 2012
INTRODUCTION: Angiogenesis represents a potential therapeutic target in breast cancer. However, responses to targeted antiangiogenic therapies have been reported to vary among patients.
François Pepin   +9 more
core   +1 more source

Vascular adhesion protein-1 expression is reduced in the intestines of infants with necrotizing enterocolitis: an observational research study

open access: yesBMC Pediatrics, 2022
Background Necrotizing enterocolitis (NEC) is an inflammatory bowel disease in preterm neonates with high morbidity and mortality. The only treatment available is supportive with broad-spectrum antibiotics and gastrointestinal rest.
Björn Andersson   +3 more
doaj   +1 more source

Gene expression signature in mouse thyroid tissue after 131I and 211At exposure [PDF]

open access: yes, 2015
BACKGROUND: (131)I and (211)At are used in nuclear medicine and accumulate in the thyroid gland and may impact normal thyroid function. The aim of this study was to determine transcriptional profile variations, assess the impact on cellular activity, and
Britta Langen   +6 more
core   +1 more source

Differential expression of AOC3 in cancer of the vulva.

open access: yes, 2021
In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of amine oxidase, copper containing 3, encoded by AOC3, in cancer of the vulva.
openaire   +2 more sources

BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4

open access: yesScientific Reports, 2021
Hepatocellular carcinoma (HCC) is one of the most prevalent and poorly responsive cancers worldwide. Bromodomain and extraterminal (BET) inhibitors, such as JQ1 and OTX-015, inhibit BET protein binding to acetylated residues in histones.
Hae In Choi   +7 more
doaj   +1 more source

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