Results 81 to 90 of about 20,895 (217)

Polygenic Risk Modelling in Periodontitis: Insights From a Feasibility Study of 4243 European Cases and Current Limitations

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background and Aim Genetic susceptibility plays a particularly important role in early‐onset (EO) and severe periodontitis (PD). The genetic risk remains largely unexplained because of limited sample sizes and heterogeneous phenotypes in genome‐wide association studies (GWAS).
Gesa M. Richter, O. Mercy Akinloye, M. Kamal Nasr, Birte Holtfreter, Alicia de Coo, Silvia Diz De Almeida, Bruno G. Loos, Søren Jepsen, Henrik Dommisch, Corinna Bruckmann, Ines Kapferer‐Seebacher, PerioGEN Cohort Group, Georg Homuth, Thomas Kocher, Henry Völzke, Klaus Berger, Matthias Laudes, Wolfgang Lieb, Nathalie van der Velde, Natasja van Schoor, Lisette de Groot, Juan Blanco, Angel Carracedo, Raquel Cruz, Astrid Dempfle, Alexander Teumer, Arne S. Schaefer, Sandra Freitag‐Wolf   +27 more
wiley   +1 more source

SGLT2i use and fracture risk compared with DPP4i in patients with T2DM

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The association between sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) use and fracture risk remains inconclusive. Most previous studies have focused on treatment‐naïve patients, despite many patients in routine clinical practice initiating SGLT2i therapy after prior dipeptidyl peptidase‐4 inhibitor (DPP4i) use.
Sung‐Yen Lin, Shih‐Hao Huang, Ching‐Han Chiang, Cheng‐Jung Ho, Chung‐Hwan Chen, Li‐Nien Chien   +5 more
wiley   +1 more source

How Alternative Management Ideas Are Realized for the Public Good: Performative Fabrics of Humanistic Practices

Journal of Management Studies, EarlyView.
Abstract Repurposing management for the public good involves realizing alternative ideas to serve societal interests. Humanistic management is centred on such ideas as human dignity and well‐being. Realization refers to the generation and maintenance of social realities corresponding to these ideas.
Oliver Laasch, Reut Livne‐Tarandach, Qing Qu, Pingping Fu, Michael Pirson   +4 more
wiley   +1 more source

Hidden in Plain Sight: Conceptualizing Platform Auxiliaries and Their Conflicting Impacts on Platforms' Value Architecture

Journal of Management Studies, EarlyView.
Abstract This paper introduces the concept of platform auxiliaries to identify a set of actors that provide independent resources explicitly designed to support complementors in their value creation and capture activities. Platform auxiliaries capitalize on unmet needs of complementors within platforms, offering services such as third‐party software ...
Donato Cutolo, Andrew Hargadon, Martin Kenney   +2 more
wiley   +1 more source

Government Orchestration at Play: The Influence of Disclosure Regulation on Stakeholder Accusations and the Role of CSR

Journal of Management Studies, EarlyView.
Abstract Government orchestration describes regulatory settings in which governments delegate some governance functions to private actors; for instance, business conduct is monitored by stakeholders under CSR disclosure regulation. This article examines the impact of this type of regulation on stakeholder monitoring, which is a core yet little‐examined
Julia Bartosch, Emma Avetisyan, Philipp A. Thompson   +2 more
wiley   +1 more source

Staphylococcus Aureus Toxins and Asthma: Pathophysiological Mechanisms, Clinical Relevance, and Therapeutic Implications in the Biologics Era

Toxins
Staphylococcus aureus frequently colonizes the skin and upper airways and produces a broad repertoire of immunomodulatory molecules. In asthma, the most consistent evidence concerns staphylococcal enterotoxins (SEs), which can act both as superantigens ...
Diego Bagnasco, Benedetta Bondi, Greta Losacco, Carola Montagnino, Francesca Froio, Elena Tedesco, Gloria D’Alessandro, Ilaria Baglivo, Laura Bruno, Sara Chiappori, Maria José Murillo Jaramillo, Marcello Mincarini, Fulvio Braido, Cristiano Caruso   +13 more
doaj   +1 more source

Navigating Regulatory Transitions: The Evolving Role of Multi‐Stakeholder Initiatives as Intermediaries in the Context of Mandatory Due Diligence Legislation

Journal of Management Studies, EarlyView.
Abstract Whereas extant studies have mostly treated multi‐stakeholder initiatives (MSIs) as instruments of private authority that interact with public governance in various spheres, this study offers an alternative view of MSIs as important regulatory intermediaries, specifically in times of regulatory flux.
Leona A. Henry, Julia Grimm, Nora Lohmeyer, Kristin Apffelstaedt, Sophie Giulini   +4 more
wiley   +1 more source

Determinants of Acute Otitis Media in Children: A Case-Control Study in West Java, Indonesia

Medicina
Background and Objectives: Acute Otitis Media (AOM) is a leading cause of morbidity in children, characterized by fever, otalgia, and hearing loss. If untreated, AOM may progress to chronic complications requiring surgical management.
Arif Dermawan, Bejo Ropii, Lina Lasminingrum, Wijana Hasansulama, Budi Setiabudiawan   +4 more
doaj   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Exploring the protective effect of silver Croton tiglium nano-extract against azoxymethane induced toxicity in female reproductive organs in rats

Heliyon
Reproductive toxicity from food and environmental contaminants has greatly affected human life. Plants are a fundamental source of bioactive components for relieving the harmful effects of pollutants.
Wael Mahmoud Aboulthana, Abd El-Nasser A. Madboli, Amal Gouda Hussien, Mohamed Seif   +3 more
doaj   +1 more source