Results 161 to 170 of about 102,386 (304)

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

Hidden in Plain Sight: Unmasking a Pseudoaneurysm Without Contrast. [PDF]

open access: yesDiagnostics (Basel)
Visonà M   +4 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

Academic Achievement Test for Anatomy of the Neck: Validity and Reliability Analysis

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Objective Anatomy education remains a fundamental component of medical and dental curricula, and mastering neck anatomy is particularly challenging due to its structural complexity and clinical relevance. Despite its importance, there is a limited number of validated instruments specifically designed to assess academic achievement in neck ...
Dilber Polat, Halil Yilmaz
wiley   +1 more source

Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge

open access: yesEquine Veterinary Education, EarlyView.
Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David   +4 more
wiley   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

open access: yesEquine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh   +4 more
wiley   +1 more source

Acute and sudden death secondary to cardiac tamponade during anaesthetic recovery in a 21‐year‐old draught mule

open access: yesEquine Veterinary Education, EarlyView.
Summary This case report is of educational value and contributes to the literature because it describes a unique death after anaesthesia due to cardiac tamponade from a rare cardiac neoplasm. In trying to diagnose the origin of chronic sinusitis, a geriatric mule mare was anaesthetised and during recovery, died acutely.
A. Carroll, J. Quandt, S. Dantino
wiley   +1 more source

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