Results 81 to 90 of about 232,794 (224)
Aortic and arterial mechanics [PDF]
Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive review is presented in the current chapter. As the function of arteries is to carry blood to the peripheral organs,
arxiv
Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao+17 more
wiley +1 more source
Introducción. La insuficiencia renal aguda es una complicación común después del reparo de un aneurisma infrarrenal de aorta abdominal; sin embargo, su incidencia es variable según el estudio y todavía existe controversia respecto a si es más frecuente ...
Mario López+5 more
doaj
Rola Ali,1– 3 Abdullah Elhosiny,1,2 Seraj Abualnaja,2,4 Ghassan Baslaim2,4 1Department of Internal Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Kingdom of Saudi Arabia; 2Department of Medicine, Fakeeh College of Medical Sciences, Jeddah, Kingdom of ...
Ali R+3 more
doaj
Endovascular repair of abdominal aortic para-anastomotic pseudoaneurysm
Para-anastomotic aneurysms are either true aneurysms or pseudoaneurysms. The latter tend to be asymptomatic until rupture. Para-anastomotic aneurysms should be approached surgically, despite the high morbidity and mortality associated with their ...
Leonardo Ghizoni Bez+3 more
doaj +1 more source
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao+15 more
wiley +1 more source
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
wiley +1 more source
Hierarchical LoG Bayesian Neural Network for Enhanced Aorta Segmentation [PDF]
Accurate segmentation of the aorta and its associated arch branches is crucial for diagnosing aortic diseases. While deep learning techniques have significantly improved aorta segmentation, they remain challenging due to the intricate multiscale structure and the complexity of the surrounding tissues.
arxiv
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao+19 more
wiley +1 more source
Fatty acid synthesis in cell-free system from rabbit aorta
The objectives of this study were to identify the subcellular fraction responsible for fatty acid synthesis in rabbit aorta and to determine the effect of cholesterol feeding on the system.
Arthur F. Whereat
doaj