Results 81 to 90 of about 742,427 (349)

Endothelial/Epithelial Mesenchymal Transition in Ascending Aortas of Patients With Bicuspid Aortic Valve

Frontiers in Cardiovascular Medicine, 2019
Thoracic aortic aneurysm (TAA) is the progressive enlargement of the aorta due to destructive changes in the connective tissue of the aortic wall. Aneurysm development is silent and often first manifested by the drastic events of aortic dissection or ...
Shohreh Maleki, Flore-Anne Poujade, Otto Bergman, Jesper R. Gådin, Nancy Simon, Karin Lång, Anders Franco-Cereceda, Simon C. Body, Hanna M. Björck, Per Eriksson   +9 more
doaj   +1 more source

The reproducibility of measuring maximum abdominal aortic aneurysm diameter from ultrasound images [PDF]

, 2021
Evan O. Matthews, Jenna Pinchbeck, Kylie Elmore, Rhondda Jones, Joseph V. Moxon, Jonathan Golledge   +5 more
openalex   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Aortic Aneurysm and Dissection : Evaluation with Spiral CT Angiography

Journal of Nepal Medical Association, 2005
The study was undertaken for aortic evaluation and to see its usefulness for assessing aortic aneurysm, aortic dissection and pseudoaneurysm by spiral CT angiography (CTA).
Umesh Kumar Sharma, M S Gulati, S Mukhopadhyay   +2 more
doaj   +1 more source

Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]

, 2012
Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany, Degani, Annamaria, Gandaglia, Alessandro, Gargiulo, Mauro, Lacabanne, Colette, Samouillan, Valérie, Spina, Michel, Stella, Andréa   +7 more
core   +2 more sources

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Mechanistic and pathological study of the genesis, growth, and rupture of abdominal aortic aneurysms [PDF]

, 2013
Postprint (published ...
Bordone, Maurizio, Loong, T. H., N.Y.Kwee, Eddy, Soudah Prieto, Eduardo, Sriram, N., Tan, C. H., Uei, P   +6 more
core   +3 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Delayed Presentation of a Giant Ascending Aortic Aneurysm following Aortic Valve Replacement

Case Reports in Medicine, 2009
Giant ascending aortic aneurysm formation following aortic valve replacement is rare. A 28-year-old man who underwent aortic valve replacement with a prosthetic valve for aortic regurgitation secondary to congenital bicuspid aortic valve about 10 years ...
Tugrul Göncü, Mustafa Sezen, Hasan Ari, Osman Tiryakioglu, Gündüz Yumun, Senol Yavuz   +5 more
doaj   +1 more source

A 103 Year Old Man With a Ruptured Abdominal Aortic Aneurysm

EJVES Vascular Forum, 2020
Introduction: With wider use of stent grafts, treating nonagenarians with abdominal aortic aneurysm has become more common in Japan. This is the report of a 103 year old patient with a ruptured abdominal aortic aneurysm who successfully underwent ...
Satoshi Nishi, Kanan Kurahashi, Takaharu Shimizu, Daisuke Arima, Akihiro Yoshimoto, Yoshihiro Suematsu   +5 more
doaj   +1 more source