Results 51 to 60 of about 726,988 (249)

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang   +8 more
wiley   +1 more source

Three-dimensional printed prototypes refine the anatomy of post-modified Norwood-1 complex aortic arch obstruction and allow presurgical simulation of the repair.

open access: yesInteractive Cardiovascular and Thoracic Surgery, 2016
Three-dimensional (3D) printed prototypes of malformed hearts have been used for education, communication, presurgical planning and simulation. We present a case of a 5-month old infant with complex obstruction at the neoaortic to transverse arch and ...
L. Kiraly, M. Tofeig, N. Jha, H. Talo
semanticscholar   +1 more source

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt   +7 more
wiley   +1 more source

Total aortic arch repair: risk factor analysis and follow-up in 199 patients.

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2016
OBJECTIVES Aortic arch surgery is associated with substantial perioperative risks. New prostheses as well as novel perfusion techniques have been developed to reduce the risks of these procedures.
A. Martens   +9 more
semanticscholar   +1 more source

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang   +4 more
wiley   +1 more source

Intraoperative ultrasound: “Alternative eye” in lymph nodal dissection in non‐small cell lung cancer

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3250-3256, December 2022., 2022
Intraoperative ultrasound of mediastinal lymph nodes allows surgeons to detect metastatic lymph nodes during surgery for NSCLC. It can show the relationship between lymph nodes and surrounding structures during biopsy, improving the safety and simplicity of the operation, increasing the number of harvested lymph nodes, and reducing the risk of ...
Gaetana Messina   +18 more
wiley   +1 more source

Do not leave the heart arrested. Non-cardioplegic continuous myocardial perfusion during complex aortic arch repair improves cardiac outcome.

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2016
OBJECTIVES Myocardial protection with cardioplegia alone may be inadequate during complex aortic arch surgery, potentially resulting in postoperative myocardial insufficiency. We hypothesized that non-cardioplegic continuous myocardial perfusion (CMP) is
A. Martens   +9 more
semanticscholar   +1 more source

Prognostic factors and genetic markers in thymic epithelial tumors: A narrative review

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3242-3249, December 2022., 2022
The aim of this review article is to discuss the different prognostic factors and genetic markers of TET and to point out discrepancies and similarities among the available literature (concerning prognostic factors) and more importantly to demonstrate the genetic pathways that could be the basis of a development of new targeted therapies.
Apostolos C. Agrafiotis   +5 more
wiley   +1 more source

Multicentre analysis of current strategies and outcomes in open aortic arch surgery: heterogeneity is still an issue.

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2016
OBJECTIVES The study was conducted to evaluate, on the basis of a multicentre analysis, current results of elective open aortic arch surgery performed during the last decade.
P. Urbanski   +13 more
semanticscholar   +1 more source

Closure of a Late‐Onset Iatrogenic Left Ventricular Pseudoaneurysm Caused by Erosion of an Apical Muscular VSD Device

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We report the case of a 3‐year‐old asymptomatic girl (12 kg, 96 cm) who was diagnosed with a large iatrogenic left ventricular pseudoaneurysm (LVP) on follow‐up ultrasound, 14 months after apical muscular ventricular septal defect (VSD) closure with a 10 mm Amplatzer Muscular VSD occluder (Abbott, USA) due to device erosion.
Raymond N. Haddad   +3 more
wiley   +1 more source

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