Results 81 to 90 of about 292,402 (288)
Advanced Science, EarlyView.Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang +9 more
wiley +1 more source
Clinical Implications of Chest X-Ray Parameters in Evaluating Patients with Cardiac Dyspnea
Eurasian Journal of Medicine, 2019 Objective: To evaluate the relationship between aortic arch calcification and clinical and radiographical parameters on chest radiography. Materials and Methods: We retrospectively evaluated 242 consecutive patients that were admitted to our ...
Elif Torun, Fehmi Kacmaz
doaj
Correlation between plasma osteopontin levels and aortic valve calcification: Potential insights into the pathogenesis of aortic valve calcification and stenosis [PDF]
, 2009 ObjectiveThe inflammatory process of aortic stenosis involves the differentiation of aortic valve myofibroblasts into osteoblasts. Osteopontin, a proinflammatory glycoprotein, both stimulates differentiation of myofibroblasts and regulates the deposition
Heretis, Katherine +13 more
core +1 more source
Advanced Science, EarlyView.Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li +14 more
wiley +1 more source
Calcification in Aging Canine Aortic Valve [PDF]
, 1986 Aging changes of aortic valves are thought to underlie the mechanism of calcification, which leads to calcific aortic stenosis in humans. The study of calcification in the aging valvular connective tissue has been hindered by the lack of a suitable ...
Trump, B. F. +3 more
core +1 more source
Cardiology Research and Practice, 2015 Low-flow low-gradient severe aortic stenosis (LFLGAS) is associated with worse outcomes. Aortic valve calcification patterns of LFLGAS as compared to non-LFLGAS have not yet been thoroughly assessed.
Barbara E. Stähli +10 more
doaj +1 more source
Early bioprosthetic valve calcification with alfacalcidol supplementation
Journal of Cardiothoracic Surgery, 2013 We report a case of early bioprosthetic valve calcification in a 76 year-old woman who had received supplementation with alfacalcidol, an analogue of vitamin D, for 3 years after her initial valve replacement.
Takano Tamaki +6 more
doaj +1 more source
Calcific Aortic Stenosis [PDF]
Circulation, 2006 Calcific aortic stenosis is the number 1 cause for surgical valve replacement in the United States and Europe. In 2006, surgical valve replacement still remains the number 1 indication for the treatment of this disease process, as defined by the American College of Cardiology/American Heart Association guidelines for valvular heart disease by Bonow et ...
openaire +1 more source
The Burden of Calcification in Dialysis Patients 1
, 2014 70 The percent of patients with significant coronary artery and aortic calcification ≈50 The percent of patients with calcified valves 50 The percent of incident dialysis patients with significant coronary calcification 50 The percent of cardiovascular ...
Vascular Calcification
core
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun +7 more
wiley +1 more source