Results 61 to 70 of about 292,402 (288)

Effect of Eccentric Calcification of an Aortic Valve on the Implant Depth of a Venus-A Prosthesis During Transcatheter Aortic Valve Replacement: A Retrospective Study

Frontiers in Physiology, 2021
ObjectOur goal was to assess the implant depth of a Venus-A prosthesis during transcatheter aortic valve replacement (TAVR) when the areas of eccentric calcification were distributed in different sections of the aortic valve.MethodsA total of 53 patients
Lanlan Li, Yang Liu, Ping Jin, Jiayou Tang, Linhe Lu, Guangyu Zhu, Chennian Xu, Chennian Xu, Yanyan Ma, Jian Yang   +9 more
doaj   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Recent Advances in Research on Human Aortic Valve Calcification

Journal of Pharmacological Sciences, 2014
Aortic valve calcification can aggravate aortic stenoses, and it is a significant cause of sudden cardiac death. The increasing number of patients with age-related calcification is a problem in developed nations.
Ken-Ichi Furukawa
doaj   +1 more source

Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. [PDF]

PLoS ONE, 2015
Simvastatin (SIM) is anti-inflammatory. We used low density lipoprotein receptor knockout (LDLR-/-) mice and human aortic smooth muscle cells (HASMCs) as model systems to study the effect of SIM on arterial calcification and to explore the potential ...
Chih-Pei Lin, Po-Hsun Huang, Chung Fang Lai, Jaw-Wen Chen, Shing-Jong Lin, Jia-Shiong Chen   +5 more
doaj   +1 more source

Gla-Rich Protein, Magnesium and Phosphate Associate with Mitral and Aortic Valves Calcification in Diabetic Patients with Moderate CKD

Diagnostics, 2022
Accelerated and premature cardiovascular calcification is a hallmark of chronic kidney disease (CKD) patients. Valvular calcification (VC) is a critical indicator of cardiovascular disease and all-cause mortality in this population, lacking validated ...
Ana P. Silva, Carla S. B. Viegas, Patrícia Guilherme, Nelson Tavares, Carolina Dias, Fátima Rato, Nélio Santos, Marília Faísca, Edgar de Almeida, Pedro L. Neves, Dina C. Simes   +10 more
doaj   +1 more source

Aortic Arch Syndrome with Cardiomegaly and Aortic Calcification

Japanese Heart Journal, 1961
Three cases of the aortic arch syndrome with cardiomegaly and aortic calcification as cardinal symptoms were reported. Fifteen necropsy cases of pulseless disease in Japan were reviewed chiefly about heart involvement, sites of lesion in vascular system and etiological consideration. These reported cases suggest that there is a heart lesion produced by
YAMADA, Hideo, HARUMI, Kenichi, OHTA, Akio, NOMURA, Takeo, OKADA, Ryozo, ISHII, Masao   +5 more
openaire   +3 more sources

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Insights on the predictive role of aortic knob calcification in post-TAVI pacemaker implantation [PDF]

Insights on the predictive role of aortic knob calcification in post-TAVI pacemaker ...
Hakan Süygün, Süygün, Hakan
core   +1 more source

Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. [PDF]

, 2012
BACKGROUND: Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known.
Makkar, Raj R, Dewey, Todd M, Pocock, Stuart, Brown, David L, Pichard, Augusto D, Bowers, Bruce, Siegel, Robert J, Smith, Craig R, Webb, John G, Tuzcu, Murat, Moses, Jeffrey W, Williams, Matthew R, Babaliaros, Vasilis C, Thourani, Vinod H, Kapadia, Samir, Svensson, Lars G, Jilaihawi, Hasan, Kodali, Susheel, Bavaria, Joseph E, MD, Fontana, Gregory P, Akin, Jodi J, Douglas, Pamela S, Bavaria, Joseph E, Herrmann, Howard C, Leon, Martin B, PARTNER Trial Investigators, Anderson, William N   +26 more
core   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source