Results 111 to 120 of about 213,227 (296)

Assessment of diastolic function in patients with aortic valve diseases

, 2019
Background: Valvular heart disease (VHD) are prevalent and impose significant impact on heart function. Diastolic Dysfunction (DD) is less appreciated than Systolic Dysfunction (SD).
Yousif, Kareem Mohsin, Khadhim Al Jaaed, Hamid Obaid   +1 more
core   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Endovascular Solutions for Aortic Arch Diseases: Total and Hybrid

, 2021
Although the endovascular approach is the therapeutic option of choice for thoracic and abdominal aortic diseases, open surgery is still the treatment of choice for aortic arch diseases.
Pacini D., Di Marco L., Lovato L., Murana G., Gliozzi G., Buia F., Attina D.   +6 more
core  

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

Advanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian, Yanrui Yang, Qiuyu Li, Ying Hu, Qin Hu, Shasha Ran, Siyu Zhou, Xiujuan Yang, Shanshan Li, Qixiong Zhang   +9 more
wiley   +1 more source

Our early and mid-term results in thoracic aorta pathologies undergoing endovascular repair

Turkish Journal of Vascular Surgery, 2019
Objectives: This study aims to present early and mid-term results of thoracic endovascular aortic repair. Patients and methods: A total of 24 male patients (mean age 63.5 years; range, 31 to 80 years) who underwent endovascular aortic repair in our ...
Sedat Ozan Karakişi, Şaban Ergene, Doğuş Hemşinli   +2 more
doaj  

Echocardiography in aortic diseases : EAE recommendations for clinical practice

, 2010
Echocardiography plays an important role in the diagnosis and follow-up of aortic diseases. Evaluation of the aorta is a routine part of the standard echocardiographic examination.
Flachskampf, Frank,, Nihoyannopoulos, Petros,, Sicari, Rosa, Erbel, Raimund, Nihoyannopoulos, Petros, Erbel, Raimund,, Vlachopoulos, Charalambos, Antonini-Canterin, Francesco, Zamorano, Jose,, Flachskampf, Frank, Rocchi, Guido,, Sicari, Rosa,, Zamorano, Jose, Antonini-Canterin, Francesco,, Vlachopoulos, Charalambos,, Evangelista, Arturo, Rocchi, Guido, Evangelista, Arturo,   +17 more
core   +1 more source

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Fluoroquinolones and Aortic Diseases: Is There a Connection

, 2019
Fluoroquinolones (FQs) are one of the most commonly prescribed classes of anti- biotics. Their high tissue distribution and broad-spectrum antibacterial coverage make their use very attractive in numerous infectious diseases.
Carino D, Elefteriades JA, Singh M, Zafar MA, Ziganshin BA   +4 more
core   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Case report: Diagnosis of a double aortic arch in the primary care setting

Journal of Family Medicine and Primary Care
A double aortic arch is a rare congenital heart anomaly not typically diagnosed in adults. It can present with nonspecific symptoms including dysphagia, a cough, and hoarseness which can lead to a delay in diagnosis or misdiagnosis.
Mary Chick
doaj   +1 more source