Results 131 to 140 of about 2,421,495 (257)
Advanced Science, EarlyView.This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang +14 more
wiley +1 more source
Aortoesophageal Fistula Mimicking Dieulafoy Disease: A Case Report
GE: Portuguese Journal of GastroenterologyIntroduction: Aortoesophageal fistula (AEF) is a rare and potentially fatal cause of upper gastrointestinal bleeding. The classic Chiari’s triad of symptoms and typical endoscopic findings are not present in all patients, making diagnosis challenging ...
Tatiana Pacheco +5 more
doaj +1 more source
In search of blood tests for thoracic aortic diseases
, 2010 A number of new diagnostic screening tools have been developed for the assessment of acute and chronic diseases of the thoracic aorta. Although standardized blood-based tests capable of detecting individuals at risk for aortic aneurysm and dissection ...
Toru Suzuki +13 more
core +1 more source
Advanced Science, EarlyView.Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li +14 more
wiley +1 more source
Engineering a Bioelectronic Hybrid Heart with Integrated Sensing and Electrical Modulation
Advanced Science, EarlyView.A bioelectronic hybrid heart is engineered by integrating iPSC‐derived cardiomyocytes, a decellularized cardiac scaffold, a cell‐laden ECM coating, and a flexible electronic mesh. The embedded electrodes enable real‐time recording of spontaneous electrical activity and localized stimulation, allowing controlled pacing and modulation of activation ...
Itai Cabilly +7 more
wiley +1 more source
Fluoroquinolones and Aortic Diseases: Is There a Connection
, 2019 Fluoroquinolones (FQs) are one of the most commonly prescribed classes of anti- biotics. Their high tissue distribution and broad-spectrum antibacterial coverage make their use very attractive in numerous infectious diseases.
Carino D +4 more
core +1 more source
Advanced Science, EarlyView.To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen +13 more
wiley +1 more source
Our early and mid-term results in thoracic aorta pathologies undergoing endovascular repair
Turkish Journal of Vascular Surgery, 2019 Objectives: This study aims to present early and mid-term results of thoracic endovascular aortic repair. Patients and methods: A total of 24 male patients (mean age 63.5 years; range, 31 to 80 years) who underwent endovascular aortic repair in our ...
Sedat Ozan Karakişi +2 more
doaj
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Recent studies suggest that immune‐mediated inflammation of perivascular adipose tissue of abdominal aortic aneurysms (AAAs) contributes to disease development and progression. Whether the perivascular adipose tissue of AAA is characterized by
Luca Piacentini +5 more
doaj +1 more source