Results 121 to 130 of about 326,342 (329)

Analysis of risk factors for new⁃onset ischemic stroke after Sun's procedure in patients with acute type A aortic dissection

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the risk factors of new⁃onset ischemic stroke in patients with acute type A aortic dissection (ATAAD) undergoing Sun's procedure.
ZHANG Chen⁃yu   +5 more
doaj   +1 more source

Bio‐Inspired Micro‐Fin‐Assisted Multi‐Modal Vascular Intervention

open access: yesAdvanced Science, EarlyView.
A magnetic guidewire with a micro‐fin–integrated tip is introduced for multimodal cardiovascular navigation. The micro‐fins exploit fluid drag to augment magnetic torque, enabling bifurcation traversal at 15 mT, tolerating 45° misalignment, bidirectional crawling, and buckle self‐correction.
Xu Liu   +8 more
wiley   +1 more source

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

open access: yesAdvanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li   +15 more
wiley   +1 more source

Next-Generation Frozen Elephant Trunk Technique in the Era of Precision Medicine

open access: yesJournal of Chest Surgery
The frozen elephant trunk (FET) technique can be applied to extensive aortic pathology, including lesions in the aortic arch and proximal descending thoracic aorta. FET is useful for tear-oriented surgery in dissections, managing malperfusion syndrome,
Suk-Won Song   +6 more
doaj   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

Computational fluid dynamics analysis of hemodynamics in bicuspid aortic valve with giant aneurysm

open access: yesJournal of Cardiothoracic Surgery
Background The current study was performed aimed at investigating the impact of bicuspid aortic valve (BAV) with a giant aneurysm of the ascending aorta (AAo) on hemodynamics within the aorta using Computational fluid dynamics (CFD), with an attempt to ...
Zhiyu Qiao   +9 more
doaj   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Image quality, contrast enhancement and radiation dose of electrocardiograph- versus non-electrocardiograph-triggered computed tomography angiography of the aorta

open access: yesSingapore Medical Journal
Introduction: Computed tomography angiography of the aorta (CTAA) is the modality of choice for investigating aortic disease. Our aim was to evaluate the image quality, contrast enhancement and radiation dose of electrocardiograph (ECG)-triggered and non-
Ying Mei Wong   +4 more
doaj   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

open access: yesAdvanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang   +8 more
wiley   +1 more source

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