Results 111 to 120 of about 881,310 (376)

Sequential ruptures of penetrating atherosclerotic ulcers of ascending aorta, aortic arch and descending thoracic aorta

open access: yesJournal of Cardiothoracic Surgery, 2020
Background Penetrating ulcers of aorta, aortic dissections and intramural hematomas all come under acute aortic syndromes and have important similarities and differences.
Pankaj Kaul   +3 more
doaj   +1 more source

Long term outcomes in men screened for abdominal aortic aneurysm : prospective cohort study [PDF]

open access: yes, 2012
PMID: 22563092 [PubMed - indexed for MEDLINE] PMCID: PMC3344734 Free PMC ArticlePeer reviewedPublisher ...
Duncan, John L   +4 more
core   +2 more sources

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
PPP1R3B induces anti‐inflammatory M2 macrophage polarization and maintains energy supply in plaques. Its absence accelerates plaque progression. PPP1R3B regulates M2 macrophage polarization and energy metabolism via phosphorylated STAT3 (p‐STAT3), which plays a dual role by activating anti‐inflammatory transcriptional programs through the PPAR‐γ/PGC‐1α/
Lin Shen   +12 more
wiley   +1 more source

Thoracic endovascular aortic repair for traumatic and non-traumatic rupture of the descending thoracic aorta: A 15-year single-centre experience

open access: yesInternational Journal of Cardiology: Heart & Vasculature
Background: Ruptures of the descending thoracic aorta are life-threatening emergencies with traumatic and non-traumatic causes. Thoracic endovascular aortic repair (TEVAR) has become a key treatment, but long-term outcome data remain limited.
Ricarda Berkenheide   +10 more
doaj   +1 more source

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

open access: yes, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario   +13 more
core   +1 more source

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng   +7 more
wiley   +1 more source

Aortic rupture

open access: yesRadiopaedia.org, 2021
Ian Bickle
semanticscholar   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Hepatocyte‐Specific GSDMD Deficiency Aggravates Sepsis by Disrupting Non‐Canonical Secretion of Anti‐Inflammatory Factors

open access: yesAdvanced Science, EarlyView.
This study proposes for the first time that hepatic GSDMD plays a key protective role in sepsis. Hepatic GSDMD may release inflammatory inhibitory factors including VEGF‐B and Gremlin‐1 through pore‐forming activity to inhibit the production of inflammatory factors from macrophages, thereby alleviating the inflammatory response of septic mice ...
Yihan Qian   +9 more
wiley   +1 more source

Delayed Surgery in a Complex Trauma Patient with Aortic Rupture, Blunt Head Trauma and Liver Laceration: a Case Report

open access: yesKaohsiung Journal of Medical Sciences, 2008
Aortic rupture is a critical condition in trauma patients. Most patients are killed at the scene of the accident. A patient who survives long enough to reach hospital also has a high risk of rupture during management.
Hsing-Lin Lin   +4 more
doaj   +1 more source

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