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Calcific Aortic Stenosis—A Review on Acquired Mechanisms of the Disease and Treatments

Frontiers in Cardiovascular Medicine, 2021
Calcific aortic stenosis is a progressive disease that has become more prevalent in recent decades. Despite advances in research to uncover underlying biomechanisms, and development of new generations of prosthetic valves and replacement techniques ...
Banafsheh Zebhi, Mohamad Lazkani, David Bark, David Bark   +3 more
doaj   +2 more sources

Moderate Aortic Stenosis With Cardiac Damage: A New Type of Severe Aortic Stenosis [PDF]

Structural Heart
The clinical implications of severe aortic stenosis have been well established. Understanding of moderate aortic stenosis, however, continues to evolve. Athough moderate aortic stenosis may be less clinically impactful in patients with normal ventricular
Nino Mihatov, MD, Philippe Pibarot, DVM, PhD   +1 more
doaj   +2 more sources

Calcific aortic stenosis [PDF]

Nature Reviews Disease Primers, 2016
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed countries. It is characterized by progressive fibro-calcific remodelling and thickening of the aortic valve leaflets that, over years, evolve to cause severe obstruction to cardiac outflow.
B. Lindman, M. Clavel, P. Mathieu, B. Iung, P. Lancellotti, C. Otto, P. Pibarot   +6 more
semanticscholar   +4 more sources

AI-powered multimodal modeling of personalized hemodynamics in aortic stenosis [PDF]

arXiv
Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However, their use is currently limited by complex workflows necessitating lengthy expert-driven manual operations.
Ozturk C, Pak DH, Rosalia L, Goswami D, Robakowski ME, McKay R, Nguyen CT, Duncan JS, Roche ET.   +8 more
arxiv   +2 more sources

Impact of severe aortic stenosis on quality of life.

PLoS ONE, 2023
IntroductionAmong individuals ≥ 65 years old, aortic stenosis is highly prevalent and the number of cases is expected to increase in the coming decades, due to the increased life expectancy.
Juan Manuel Gracia Baena, Josep Ramon Marsal Mora, Sara Llorca Cardeñosa, Imma Calaf Vall, Marta Zielonka, Pere Godoy   +5 more
doaj   +2 more sources

Moderate Aortic Stenosis in Patients With Heart Failure

Korean Circulation Journal, 2022
Author's summary Moderate aortic stenosis with concomitant heart failure portends a significantly worse prognosis in both preserved and reduced left ventricular ejection fraction.
V. Truong, John Ernst, Akhil Pallerla, Amitesh Verma, C. Bartone, C. Palmer, E. Chung   +6 more
semanticscholar   +1 more source

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

European Heart Journal, 2022
Graphical Abstract Graphical abstract Key points from the 2022 Lp(a) consensus statement. Current evidence demonstrates a causal continuous association in different ethnicities between Lp(a) concentration and cardiovascular outcomes including aortic ...
F. Kronenberg, S. Mora, E. Stroes, B. Ference, B. Arsenault, L. Berglund, M. Dweck, M. Koschinsky, G. Lambert, F. Mach, C. McNeal, P. Moriarty, P. Natarajan, B. Nordestgaard, K. Parhofer, S. Virani, A. von Eckardstein, G. Watts, Jane K. Stock, K. Ray, L. Tokgözoğlu, A. Catapano   +21 more
semanticscholar   +1 more source

Cardiac amyloidosis and aortic stenosis: a state-of-the-art review

European Heart Journal Open, 2023
Cardiac amyloidosis is caused by the extracellular deposition of amyloid fibrils in the heart, involving not only the myocardium but also any cardiovascular structure.
Vikash Jaiswal, Vibhor Agrawal, Yashita Khulbe, Muhammad Hanif, Helen Huang, Maha Hameed, A. Shrestha, F. Perone, Charmy Parikh, Sabas Ivan Gomez, K. Paudel, Jerome S. Zacks, Kendra J. Grubb, S. De Rosa, Alessia Gimelli   +14 more
semanticscholar   +1 more source

Moderate Aortic Stenosis: What is it and When Should We Intervene?

Interventional Cardiology: Reviews, Research, Resources, 2021
Current guidelines recommend aortic valve replacement in patients with severe aortic stenosis in the presence of symptoms or a left ventricular ejection fraction
Sveeta Badiani, Sanjeev Bhattacharyya, Nikoo Aziminia, Thomas A Treibel, Guy Lloyd   +4 more
doaj   +1 more source

Prognosis of hemodialysis patients with progressive aortic stenosis: a prospective cohort study

Renal Replacement Therapy, 2021
Background Whether progressive mild to moderate aortic stenosis in hemodialysis patients influences their prognosis has not been elucidated. This prospective cohort study explored whether progressive aortic stenosis predicted the rate of cardiac events ...
Yoriko Horiguchi, Kaoru Uemura, Naoyoshi Aoyama, Shinichi Nakajima, Tomoki Asai, Sachiko Motohashi, Manae Harada, Maoko Ida, Atsushi Yoshida   +8 more
doaj   +1 more source