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Calcific Aortic Stenosis—A Review on Acquired Mechanisms of the Disease and Treatments

Frontiers in Cardiovascular Medicine, 2021
Calcific aortic stenosis is a progressive disease that has become more prevalent in recent decades. Despite advances in research to uncover underlying biomechanisms, and development of new generations of prosthetic valves and replacement techniques ...
Banafsheh Zebhi, Mohamad Lazkani, David Bark, David Bark   +3 more
doaj   +2 more sources

Congenital aortic stenosis due to unicuspid unicommissural aortic valve: a case report [PDF]

Journal of Cardiothoracic Surgery, 2018
Background Unicuspid unicommissural aortic valve is an extremely rare congenital anomaly that usually presents in adulthood but can rarely present in infancy.
Arnar B. Ingason, Gunnlaugur Sigfusson, Bjarni Torfason   +2 more
doaj   +4 more sources

Impact of severe aortic stenosis on quality of life

PLoS ONE, 2023
Introduction Among individuals ≥ 65 years old, aortic stenosis is highly prevalent and the number of cases is expected to increase in the coming decades, due to the increased life expectancy.
Juan Manuel Gracia Baena, Josep Ramon Marsal Mora, Sara Llorca Cardeñosa, Imma Calaf Vall, Marta Zielonka, Pere Godoy   +5 more
doaj   +2 more sources

Prognosis of hemodialysis patients with progressive aortic stenosis: a prospective cohort study

Renal Replacement Therapy, 2021
Background Whether progressive mild to moderate aortic stenosis in hemodialysis patients influences their prognosis has not been elucidated. This prospective cohort study explored whether progressive aortic stenosis predicted the rate of cardiac events ...
Yoriko Horiguchi, Kaoru Uemura, Naoyoshi Aoyama, Shinichi Nakajima, Tomoki Asai, Sachiko Motohashi, Manae Harada, Maoko Ida, Atsushi Yoshida   +8 more
doaj   +1 more source

Moderate Aortic Stenosis: What is it and When Should We Intervene?

Interventional Cardiology: Reviews, Research, Resources, 2021
Current guidelines recommend aortic valve replacement in patients with severe aortic stenosis in the presence of symptoms or a left ventricular ejection fraction
Sveeta Badiani, Sanjeev Bhattacharyya, Nikoo Aziminia, Thomas A Treibel, Guy Lloyd   +4 more
doaj   +1 more source

Maximal Aortic Valve Cusp Separation and Severity of Aortic Stenosis [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: An integrated approach that incorporates two dimensional, M mode and Doppler echocardiographic evaluation has become the standard means for accurate quantification of severity of valvular aortic stenosis.
K Jayaprakash, VP Dilu, Raju George
doaj   +1 more source

Clinical Outcomes in High‐Gradient, Classical Low‐Flow, Low‐Gradient, and Paradoxical Low‐Flow, Low‐Gradient Aortic Stenosis After Transcatheter Aortic Valve Implantation: A Report From the SwissTAVI Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background In view of the rising global burden of severe symptomatic aortic stenosis, its early recognition and treatment is key. Although patients with classical low‐flow, low‐gradient (C‐LFLG) aortic stenosis have higher rates of death after ...
Max Wagener, Oliver Reuthebuch, Dik Heg, David Tüller, Enrico Ferrari, Jürg Grünenfelder, Christoph Huber, Igal Moarof, Olivier Muller, Fabian Nietlispach, Stéphane Noble, Marco Roffi, Maurizio Taramasso, Christian Templin, Stefan Toggweiler, Peter Wenaweser, Stephan Windecker, Stefan Stortecky, Raban Jeger   +18 more
doaj   +1 more source

A model based on clinical parameters to identify myocardial late gadolinium enhancement by magnetic resonance in patients with aortic stenosis: An observational study [PDF]

, 2020
Objective With increasing age, the prevalence of aortic stenosis grows exponentially, increasing left heart pressures and potentially leading to myocardial hypertrophy, myocardial fibrosis and adverse outcomes.
Alpendurada, Francisco, Dweck, Marc, Kuk, Mariya, Newsome, Simon, Pennell, Dudley J, Prasad, Sanjay K, Vassiliou, Vassilios S   +6 more
core   +1 more source

Ubiquitin-specific protease as the underlying gene biomarker for aortic stenosis

Lipids in Health and Disease, 2020
Background Aortic stenosis is a common heart valvular disease whose pathological processes include an inflammatory reaction and lipid accumulation. However, its detailed pathogenesis is yet to be completely elucidated.
Yin Yang, Lian-qun Wang, Bo-chen Yao, Zhi-gang Guo   +3 more
doaj   +1 more source

Effects of aerobic exercise on cardiac function and gene expression of NADPH oxidases in diaphragm muscle of rats with aortic stenosis-induced heart failure

Frontiers in Physiology, 2023
We evaluated the influence of aerobic physical exercise (EX) on gene-encoding proteins associated with oxidative stress in diaphragm muscle of rats with aortic stenosis-induced heart failure (HF).
Mariana Janini Gomes, Ana Karenina Sabela, Ana Karenina Sabela, Isabele Tiburcio Pecin Ferreira, Sérgio Luiz Borges de Souza, Gustavo Augusto Ferreira Mota, Vitor Loureiro da Silva, Dijon Henrique Salomé de Campos, Aline Regina Ruiz Lima, Marianna Rabelo Carvalho, Silmeia Garcia Zanati Bazan, Camila Renata Corrêa, Antônio Carlos Cicogna, Marina Politi Okoshi, Francis Lopes Pacagnelli, Francis Lopes Pacagnelli   +15 more
doaj   +1 more source