Results 141 to 150 of about 71,731 (296)

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

Decreased Aortic Elasticity in Noncompaction Cardiomyopathy Compared to Dilated Cardiomyopathy

Journal of Cardiovascular Development and Disease
Abnormal aortic elasticity serves as a marker for cardiovascular mortality and has a negative impact on the left ventricular (LV) afterload. Noncompaction cardiomyopathy (NCCM) is characterized by hypertrabeculation of the LV endomyocardial wall, with an
Martijn Tukker, Sharida Mohamedhoesein, Emrah Kaya, Arend F.L. Schinkel, Kadir Caliskan   +4 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Aortic Stiffness

Journal of the American College of Cardiology, 2015
Harbaoui, Brahim, Courand, Pierre-Yves, Girerd, Nicolas, Lantelme, Pierre   +3 more
openaire   +1 more source

Analysis of Pulsatile Vessel Expansion in Healthy, COPD‐and PH‐Patients Using Dynamic Vessel Segmentation in Free‐Breathing Lung MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The pulsatile expansion of pulmonary vessels carries dynamic cardiopulmonary information that may reveal disease earlier than structural changes alone. Purpose To test (i) intra‐ and inter‐scan repeatability of dynamic vessel metrics in healthy subjects, and (ii) whether chronic obstructive pulmonary disease (COPD) and postcapillary
Julian Glandorf, Marius M. Klein, Filip Klimeš, Agilo Luitger Kern, Marcel Gutberlet, Jens M. Hohlfeld, Marius M. Hoeper, Karen M. Olsson, Frank Wacker, Jens Vogel‐Claussen, Andreas Voskrebenzev   +10 more
wiley   +1 more source

Aortic frequency response determination via bioimpedance plethysmography

, 2019
Objective: Arterial stiffness is an important marker to predict cardio vascular events. Common measurement techniques to determine the condition of the aorta are limited to the acquisition of the arterial pulse wave at the extremities.
Hauschild, Sebastian, Kusche, Roman, Lindenberg, Arthur-Vincent, Ryschka, Martin   +3 more
core   +1 more source

Pre‐ and Post‐Interventional Hemodynamic Characterization of the Femoropopliteal Artery Using Vector Flow Imaging in Peripheral Arterial Occlusive Disease

Journal of Ultrasound in Medicine, EarlyView.
Objectives The femoropopliteal (FP) artery is the most frequently revascularized segment in peripheral artery disease (PAD), followed by the iliac segment. Wall shear stress (WSS) is a key local factor implicated in both atherosclerotic plaque formation and restenosis after angioplasty.
Jan Lukas Prüser, Gisela Winkelbauer, Wulf Dieker, Abdulkader Adler, Klaus Amendt, Martin Sigl   +5 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial

International Journal of COPD, 2015
Michelle E John,1 John R Cockcroft,2 Tricia M McKeever,3 William R Coward,1 Dennis J Shale,2 Simon R Johnson,1 Jim G Thornton,4 Timothy W Harrison,1 Alan J Knox,1 Charlotte E Bolton1 1Nottingham Respiratory Research Unit, School of Medicine, University ...
John ME, Cockcroft JR, McKeever TM, Coward WR, Shale DJ, Johnson SR, Thornton JG, Harrison TW, Knox AJ, Bolton CE   +9 more
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