Results 101 to 110 of about 1,048,768 (410)

Quadricuspid aortic valve [PDF]

European Journal of Cardio-Thoracic Surgery, 2012
Daniel Hanratty*, Olatunde Farode, Adrian Ionescu and Aprim Youhana a Department of Cardiothoracic Surgery, Morriston Hospital, Swansea, UK b Department of Cardiology, Morriston Hospital, Swansea, UK * Corresponding author. 34 St Stephens Mansions, Mount Stuart Square, Cardiff CF10 5LQ, UK.
Aprim Youhana, Adrian Ionescu, Olatunde Farode, Daniel Hanratty   +3 more
openaire   +3 more sources

Effect Of Coronary Bypass And Valve Structure On Outcome In Isolated Valve Replacement For Aortic Stenosis [PDF]

, 2012
Reports differ regarding the effect of concomitant coronary artery bypass grafting (CABG) in patients who undergo aortic valve replacement (AVR) for aortic stenosis (AS), and no reports have described the effect of aortic valve structure in patients who ...
Filardo, Giovanni, Hamman, Baron Lloyd, Hebeler, Robert Frederick, Henry, Albert Carl, Ko, Jong Mi, Matter, Gregory John, Roberts, Carey Camille, Roberts, William Clifford, Vowels, Travis James   +8 more
core   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Contemporary Outcomes in Low‐Gradient Aortic Stenosis Patients Who Underwent Dobutamine Stress Echocardiography

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Detection of flow reserve (FR) by dobutamine stress echocardiography is used for risk stratification in low‐gradient aortic stenosis (AS).
Kimi Sato, Kesavan Sankaramangalam, Krishna Kandregula, Jennifer A. Bullen, Samir R. Kapadia, Amar Krishnaswamy, Stephanie Mick, L. Leonardo Rodriguez, Richard A. Grimm, Venu Menon, Milind Y. Desai, Lars G. Svensson, Brian P. Griffin, Zoran B. Popović   +13 more
doaj   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Ascending aortic aneurysm and aortic valve dysfunction in bicuspid aortic valve disease

, 2013
BACKGROUND: The relationship of aortic valve dysfunction and ascending aortic aneurysm is unclear in adults with bicuspid aortic valve disease. METHODS: We retrospectively studied 134 consecutive out-patients (98 men, 36 women aged 43+/-18years) with ...
Aydin, A., Berger, J., Bernhardt, A., Desai, N., Detter, C., Hillebrand, M., Lorenzen, V., Meinertz, T., Mortensen, K., Reichenspurner, H., Robinson, P., Rybczynski, M., Sheikhzadeh, S., Treede, H., von Kodolitsch, Y., Willems, S.   +15 more
core   +1 more source

A comprehensive review of the PARTNER trial [PDF]

, 2013
ObjectivePercutaneous transcatheter aortic valve replacement was introduced in 2002, but its effectiveness remained to be assessed.MethodsA prospective, randomized trial (the Placement of Aortic Transcatheter Valves, or PARTNER) was designed with 2 arms:
Blackstone, Eugene H., Gillinov, A. Marc, Kapadia, Samir, Lytle, Bruce W., Roselli, Eric E., Sabik, Joseph F., Svensson, Lars G., Tuzcu, Murat   +7 more
core   +1 more source

Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis.

European Heart Journal, 2019
AIMS Owing to new evidence from randomized controlled trials (RCTs) in low-risk patients with severe aortic stenosis, we compared the collective safety and efficacy of transcatheter aortic valve implantation (TAVI) vs.
G. Siontis, P. Overtchouk, T. Cahill, T. Modine, B. Prendergast, F. Praz, T. Pilgrim, T. Petrinic, A. Nikolakopoulou, G. Salanti, L. Søndergaard, S. Verma, P. Jüni, S. Windecker   +13 more
semanticscholar   +1 more source

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source

Follow-Up Report of Patients With Moderate Aortic Valve Regurgitation After Cardiac Surgery [PDF]

Texas Heart Institute Journal
Background: The appropriateness of aortic valve surgery for patients with moderate aortic valve regurgitation undergoing coronary artery bypass graft (CABG), mitral valve replacement (MVR), or both is uncertain.
Arezou Zoroufian, MD, Arya Afrooghe, MD, Manouchehr Ziafat, MD, Arash Jalali, PhD, Mohammadreza Babaei, MD, Pooria Ahmadi, MD, Hakimeh Sadeghian, MD   +6 more
doaj   +1 more source