Results 211 to 220 of about 525,140 (261)

Mock Circulatory Loop With Autoregulated Renal Circulation Based on Perfusion Pressure for Circulatory Support Devices Evaluation

open access: yesArtificial Organs, EarlyView.
Renal autoregulation based on perfusion pressure, defined as the difference between mean arterial pressure and central venous pressure, was successfully implemented in a mock circulatory loop. This provides a platform to assess cardiovascular devices and therapies that may affect both pressures differently, such as ECMO support and intravenous fluid ...
Eden Kharrouba   +5 more
wiley   +1 more source

Prenatal Presentation of Muggenthaler‐Chowdhury‐Chioza Syndrome Caused by Compound Heterozygous Variants in HYAL2

open access: yes
Prenatal Diagnosis, EarlyView.
Pauline Planté‐Bordeneuve   +7 more
wiley   +1 more source

A pro‐inflammatory cytokine signature characterises thrombotic antiphospholipid syndrome despite stable anticoagulation

open access: yesBritish Journal of Haematology, EarlyView.
Primary antiphospholipid syndrome comprises distinct inflammatory subgroups defined by cytokine profiling. A shared pro‐inflammatory signature is present across all patients, whereas arterial thrombosis demonstrates enhanced inflammatory activation compared with venous thrombosis, suggesting divergent pathogenic mechanisms and opportunities for ...
Catherine B. Ducker   +6 more
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer   +5 more
wiley   +1 more source

Midterm Clinical and Echocardiographic Outcomes After Transcatheter Aortic Valve Replacement in Patients With Severe Bicuspid Aortic Valve Stenosis. [PDF]

open access: yesJ Am Heart Assoc
Nienaber S   +15 more
europepmc   +1 more source

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro   +3 more
wiley   +1 more source

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