Results 31 to 40 of about 1,048,768 (410)
Presence Of A Congenitally Bicuspid Aortic Valve Among Patients Having Combined Mitral And Aortic Valve Replacement [PDF]
, 2012 Although bicuspid aortic valve occurs in an estimated 1% of adults and mitral valve prolapse in an estimated 5% of adults, occurrence of the 2 in the same patient is infrequent.
Hamman, Baron Lloyd +5 more
core +1 more source
Transcatheter Aortic‐Valve Replacement with a Self‐Expanding Valve in Low‐Risk Patients
New England Journal of Medicine, 2019 BACKGROUND Transcatheter aortic‐valve replacement (TAVR) is an alternative to surgery in patients with severe aortic stenosis who are at increased risk for death from surgery; less is known about TAVR in low‐risk patients.
J. Popma +30 more
semanticscholar +1 more source
Controlled Comparison of Simulated Hemodynamics across Tricuspid and Bicuspid Aortic Valves [PDF]
, 2021 Bicuspid aortic valve is the most common congenital heart defect, affecting 1-2% of the global population. Patients with bicuspid valves frequently develop dilation and aneurysms of the ascending aorta. Both hemodynamic and genetic factors are believed to contribute to dilation, yet the precise mechanism underlying this progression remains under debate.
arxiv +1 more source
Medicine, 2002 Abstract Aortic valve disease encompasses aortic stenosis, aortic regurgitation, and congenital malformations. Aortic valve stenosis is a common problem among the elderly, and valve replacement is still the only treatment option for severe symptomatic disease.
Catherine M Otto, Jason P. Linefsky
openaire +2 more sources
European Heart Journal, 2020 AIMS Transcatheter aortic valve implantation (TAVI) has emerged as established treatment option in patients with symptomatic aortic stenosis. Technical developments in valve design have addressed previous limitations such as suboptimal deployment ...
H. Thiele +26 more
semanticscholar +1 more source
Clinical overview on RASopathies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022 Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
Frontiers in Physiology, 2017 Bicuspid aortic valve (BAV) is a common congenital cardiac malformation affecting 1–2% of people. BAV results from fusion of two adjacent aortic valve cusps, and is associated with dilatation of the aorta, known as bicuspid valve associated aortopathy ...
Ali Fatehi Hassanabad +8 more
doaj +1 more source
The hemodynamics of transcatheter aortic valves in transcatheter aortic valves
The Journal of Thoracic and Cardiovascular Surgery, 2021 The durability of transcatheter aortic valves (TAVs) remains their greatest disadvantage, given that fixed tissue leaflets are not immune to structural degeneration from calcification and thrombosis. Therefore, a second intervention is necessary, especially given that TAV in low-risk patients has shown noninferior outcomes compared with surgery.
Scott Lilly +4 more
openaire +4 more sources
The living aortic valve: From molecules to function. [PDF]
, 2014 The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle.
Bertazzo, S +5 more
core +1 more source
PATHOPHYSIOLOGY, INVESTIGATIONS, AND TREATMENT OF PATIENTS WITH BICUSPID AORTIC VALVE [PDF]
, 2022 Bicuspid aortic valve is a congenital anomaly of the heart in which the aortic valve has two loops instead of the normal three. It causes valve degeneration and is associated with dilation of the aorta.
ABD AL-RAZIK, ASHRAF HAMADA +5 more
core +2 more sources