Results 21 to 30 of about 574,230 (187)

Mechanical injury accentuates lipid deposition in ApoE–/– mice and advance aortic valve stenosis: A novel modified aortic valve stenosis model

Frontiers in Cardiovascular Medicine, 2023
BackgroundCurrent mouse models still have limitations in studying aortic valve stenosis (AVS). A suitable animal model bearing a close resemblance to the pathophysiological processes of humans needs to be developed.
Dezhong Wen, Li Hu, Jianggui Shan, Hengyuan Zhang, Liuhua Hu, Ancai Yuan, Jun Pu, Song Xue   +7 more
doaj   +1 more source

Aortic stenosis: From diagnosis to optimal treatment [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2008
Aortic stenosis is the most frequent valvular heart disease. Aortic sclerosis is the first characteristic lesion of the cusps, which is considered today as the process similar to atherosclerosis. Progression of the disease is an active process leading to
Tavčiovski Dragan, Davičević Žaklina
doaj   +1 more source

Correlation Between Aortic Valve Sclerosis and Coronary Artery Disease: A Cross - Sectional Study [PDF]

Journal of Cardio-Thoracic Medicine, 2013
Introduction: Aortic valve sclerosisis considered as a manifestation of coronary atherosclerosis. Recent studies demonstrated an association between aortic valve sclerosis and obstructive coronary artery disease.
Afsoon Fazlinezhad, Leila Hosseini, Hadis Yousefzadeh, Saied Akhlaghi   +3 more
doaj   +2 more sources

Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models

Frontiers in Cardiovascular Medicine, 2021
Background: Calcific aortic valve disease is common in the aging population and is characterized by the histological changes of the aortic valves including extracellular matrix remodeling, osteochondrogenic differentiation, and calcification.
Subramanian Dharmarajan, Mei Y. Speer, Kate Pierce, Jake Lally, Elizabeth M. Leaf, Mu-En Lin, Marta Scatena, Cecilia M. Giachelli   +7 more
doaj   +1 more source

The Contribution of Whole Blood Viscosity to the Process of Aortic Valve Sclerosis. [PDF]

Med Princ Pract, 2018
<b><i>Objective:</i></b> We aimed to investigate whether increased whole blood viscosity (WBV) could be an important factor for the occurrence of aortic valve sclerosis (AVS). <b><i>Subjects and Methods:</i></b> A total of 209 patients were enrolled in the study.
Sercelik A, Besnili AF.
europepmc   +4 more sources

Relationship Between Platelet Indices and Aortic Valve Sclerosis [PDF]

Clinical and Applied Thrombosis/Hemostasis, 2009
Objective: Aortic valve sclerosis (AVS) is a progressive disease that is characterized by aortic valve thickening without causing significant narrowing and in which pathology resembles atherosclerotic coronary heart disease. We aimed to evaluate the relationship between AVS and platelet indices including mean platelet volume (MPV), platelet ...
Murat, Sucu, Vedat, Davutoglu, Ibrahim, Sari, Orhan, Ozer, Mehmet, Aksoy   +4 more
openaire   +2 more sources

Cholesterol efflux promoting function of high-density lipoproteins in calcific aortic valve stenosis

Atherosclerosis Plus, 2021
Background and aims: Cholesterol efflux capacity is a functional property of high-density lipoproteins (HDL) reflecting the efficiency of the atheroprotective reverse cholesterol transport process in humans.
Duygu Kocyigit, Francesca Zimetti, Kadri M. Gurses, Ilaria Zanotti, Cinzia Marchi, Marcus Ståhlman, Jan Borén, Hande Canpinar, Mehmet F.T. Soyal, Dicle Guc, Tuncay Hazirolan, Necla Ozer, Lale Tokgozoglu   +12 more
doaj   +1 more source

Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. [PDF]

, 2012
BACKGROUND: Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known.
Makkar, Raj R, Dewey, Todd M, Pocock, Stuart, Brown, David L, Pichard, Augusto D, Bowers, Bruce, Siegel, Robert J, Smith, Craig R, Webb, John G, Tuzcu, Murat, Moses, Jeffrey W, Williams, Matthew R, Babaliaros, Vasilis C, Thourani, Vinod H, Kapadia, Samir, Svensson, Lars G, Jilaihawi, Hasan, Kodali, Susheel, Bavaria, Joseph E, MD, Fontana, Gregory P, Akin, Jodi J, Douglas, Pamela S, Bavaria, Joseph E, Herrmann, Howard C, Leon, Martin B, PARTNER Trial Investigators, Anderson, William N   +26 more
core   +1 more source

Association between red blood cell distribution width and aortic valve sclerosis

Medicine Science, 2020
RDW is a simple and inexpensive parameter, which reflects the degree of anisocytosis. Evidence from recent studies indicates that anisocytosis is common in most of the cardiovascular diseases and is related to their prognosis.
Kader Eliz Uzel, Hatice Selcuk, Sezen Baglan Uzunget, Mehmet Timur Selcuk   +3 more
doaj   +1 more source

Pitfalls and Tips in the Assessment of Aortic Stenosis by Transthoracic Echocardiography

Diagnostics, 2023
Aortic stenosis (AS) is a valvular heart disease that significantly contributes to cardiovascular morbidity and mortality worldwide. The condition is characterized by calcification and thickening of the aortic valve leaflets, resulting in a narrowed ...
Grazia Canciello, Shabnam Pate, Anna Sannino, Felice Borrelli, Gaetano Todde, Paul Grayburn, Maria-Angela Losi, Giovanni Esposito   +7 more
doaj   +1 more source