Results 31 to 40 of about 16,952 (210)

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. [PDF]

, 2018
Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues, including atherosclerotic lesions, and frequently mediate proinflammatory changes 1 .
Binder, Christoph J, Bowden, Karen, Diehl, Cody, Gaddis, Dalia E, Glass, Christopher K, Gonen, Ayelet, Hedrick, Catherine C, Hung, Ming-Yow, Ley, Klaus, MacDonald, Jeffrey G, Mellon, Pamela L, Miller, Yury I, Määttä, Antti, Pattison, Jennifer, Peterson, Kirk L, Prohaska, Thomas A, Que, Xuchu, Sun, Xiaoli, Tsimikas, Sotirios, Witztum, Joseph L, Yeang, Calvin, Ylä-Herttuala, Seppo   +21 more
core   +1 more source

Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]

, 2015
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core   +8 more sources

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model [PDF]

, 2017
Aortic valve disease (AVD) is a common condition with a progressive natural history, and presently, there are no pharmacologic treatment strategies. Elastic fiber fragmentation (EFF) is a hallmark of AVD, and increasing evidence implicates developmental ...
Aikawa, Barnette, Basalyga, Bonow, Brown-Augsburger, Brunskill, Brunskill, Chung, Fondard, Franco, Gallegos, Gapski, Ghosh, Gu, Helske, Hinton, Hinton, Holm, Ihn, Iverson, Jensen, Keane, Krenz, Liang, Lindeman, Marshall, Mercer, Mohler, Mozaffarian, Munjal, Nishimura, Nkomo, Perrotta, Poggio, Potter, Rajamannan, Rossebo, Sauls, Schmieder, Schoen, Starcher, Vesely, Wirrig, Wylie-Sears, Xiong, Xiong   +45 more
core   +2 more sources

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I, Ellinwood, N Matthew, Kakkis, Emil D, Lyons, Jeremiah A, McEntee, Michael F, Passage, Merry B, Wall, Jonathan S   +6 more
core   +3 more sources

C-reactive protein in degenerative aortic valve stenosis

Cardiovascular Ultrasound, 2006
Degenerative aortic valve stenosis includes a range of disorder severity from mild leaflet thickening without valve obstruction, "aortic sclerosis", to severe calcified aortic stenosis.
Mazzone AnnaMaria, Sanchez Pedro L
doaj   +1 more source

Regular exercise or changing diet does not influence aortic valve disease progression in LDLR deficient mice. [PDF]

PLoS ONE, 2012
BACKGROUND: The development and progression of calcific aortic valve disease (CAVD) shares a number of similarities with atherosclerosis. Recently we could demonstrate that regular exercise training (ET) as primary prevention prevents aortic valve ...
Florian Schlotter, Yasuharu Matsumoto, Norman Mangner, Gerhard Schuler, Axel Linke, Volker Adams   +5 more
doaj   +1 more source

Real-time imaging required for optimal echocardiographic assessment of aortic valve calcification [PDF]

, 2012
Introduction Aortic valve calcification (AVC), even without haemodynamic significance, may be prognostically import as an expression of generalized atherosclerosis, but techniques for echocardiographic assessment are essentially unexplored.
Caidahl, K., Eriksson, M.J., Eriksson, P., Franco-Cereceda, A., Gustavsson, Tomas, Liska, J., Petrini, J., Prahl, U., Rickenlund, A., Yousry, M.   +9 more
core   +1 more source

Gene expression profiling of human calcific aortic valve disease

Genomics Data, 2016
Calcific aortic valve disease is a slowly progressive disorder that ranges from mild valve thickening (i.e. aortic sclerosis) to severe calcification of valves (i.e. aortic stenosis).
Jaana Rysä
doaj   +1 more source

Calcific aortic valve disease and hypertension [PDF]

, 2008
This review addresses the role of hypertension in precipitating Calcific aortic valve disease (CAVD) and the therapeutic potential of anti-hypertensive interventions to ameliorate CAVD.
Ballinger, M, Dadlani, H, Little, P, Marasco, S, Osman, N   +4 more
core   +1 more source

Mild aortic valve disease and the diastolic pressure–volume relationship in heart failure with preserved ejection fraction

Open Heart, 2021
Objective Mild aortic valve stenosis (AS) and aortic valve (AV) sclerosis are associated with diastolic dysfunction and increased mortality in the general population.
Mackram F Eleid, Barry A Borlaug, Yogesh N V Reddy, Grace Lin, Daniel Burkhoff, Frederik H Verbrugge   +5 more
doaj   +1 more source