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Inherited aortopathy: an overview

British Journal of Cardiac Nursing, 2023
This article is the fourth instalment of a wider series looking at cardiac genetic concepts. Inherited aortopathies are a group of syndromic and non-syndromic genetic conditions that affect the aorta. Aortopathies can lead to sudden cardiac death through aortic aneurysm rupture, especially in individuals whose aortopathy is undiagnosed.
Fortunate Mamombe   +7 more
openaire   +1 more source

Aortopathy in Congenital Heart Disease

Cardiology Clinics, 2020
Aortic dilatation is common in patients with congenital heart disease and is seen in patients with bicuspid aortic valve and those with conotruncal congenital heart defects. It is important to identify patients with bicuspid aortic valve at high risk for aortic dissection.
Timothy B, Cotts   +3 more
openaire   +2 more sources

Aortopathy in pregnancy

Seminars in Perinatology, 2014
Up to half of all aortic dissections and ruptures in women younger than 40 years are associated with pregnancy. In pregnancy, women with aortic disease such as arteritis and aortitis are at significant risk of aneurysmal formation and dissection with potential for catastrophic outcomes.
openaire   +2 more sources

Bicuspid aortic valve related aortopathy

General Thoracic and Cardiovascular Surgery, 2017
Bicuspid aortic valve related aortopathy is known to significantly increase the risk for catastrophic aortic events and, therefore, represents a considerable health burden. Albeit of ongoing research in this field including genetic, molecular, hemodynamic and morphologic aspects, bicuspid aortic valve related aortopathy still represents an imperfectly ...
Salah A Mohamed
exaly   +3 more sources

Idiopathic medial aortopathy and arteriopathy

The American Journal of Medicine, 1968
Abstract Five patients showing similar lesions in the aorta and its great branches are described. All showed patchy destruction of the elastic and muscle fibers of the media, with secondary fibrosis of the intima and sometimes of the adventitia. None had clinical or serologic evidence of syphilis.
Y, Marquis   +3 more
openaire   +2 more sources

Aortopathy: Effects of Lipid-Lowering Therapy

Cardiology in Review, 2023
Aortopathies can be congenital or acquired. Aortic atherosclerosis, abdominal aortic aneurysm, and degenerative aortic stenosis are some of the major manifestations of acquired aortopathy. Dyslipidemia, an imbalance of plasma lipid levels, is strongly associated with common aortopathies.
Matthew, Vollaro   +4 more
openaire   +2 more sources

Stenting in Aortopathies

2017
Transcatheter stent deployment within the aorta is generally used for two purposes: (1) relief of aortic obstruction as seen in aortic coarctation and (2) the use of covered stents to exclude an aneurysm or pseudoaneurysm of the aorta. For the purpose of relieving obstruction, balloon angioplasty alone is associated with reasonable short-term ...
Joanna Ghobrial, Jamil Aboulhosn
openaire   +1 more source

Update on bicuspid aortic valve aortopathy

Current Opinion in Cardiology, 2017
The appropriate treatment of bicuspid aortic valve (BAV)-associated aortopathy is still controversial. We aimed to summarize recent evidence from the literature that focused on the prediction of aortopathy progression and adverse aortic events.Following the detailed description of valvulo-aortic phenotypes in BAV disease in the previous imaging studies,
Girdauskas, Evaldas, Petersen, Johannes
openaire   +3 more sources

Genetic testing for aortopathies

Current Opinion in Cardiology, 2019
Although the majority of thoracic aortic aneurysms and dissections (TAD) in the overall population are mainly related to arterial hypertension and atherosclerosis, Heritable Thoracic Aortic Disease (HTAD) are increasingly recognized, especially in younger individuals.
De Backer, Julie   +2 more
openaire   +3 more sources

Aortopathy in Marfan syndrome: an update

Cardiovascular Pathology, 2014
Marfan syndrome (MFS) is an inherited autosomal dominant multisystem disease caused by mutations in the FBN1 gene encoding fibrillin-1, an extracellular matrix glycoprotein widely distributed in mesenchymal-derived tissues that provide a scaffold for elastin deposition.
Romaniello, F   +7 more
openaire   +3 more sources

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