Results 31 to 40 of about 2,098 (173)
When Fever Defies Diagnosis: Wissler-Fanconi Syndrome as an Atypical Presentation of Adult-Onset Still's Disease. [PDF]
Clin Case RepABSTRACT Adult‐onset Still's disease should be considered in young adults presenting with fever of unknown origin and inflammatory arthritis, even in the absence of rash or sore throat. Recognition of the Wissler–Fanconi variant and early ferritin testing can prevent diagnostic delay and enable prompt, effective immunosuppressive therapy.
Najeeb A +5 more
europepmc +2 more sources
Myositis, Vasculitis, Hepatic Dysfunction in Adult-Onset Still's Disease
Case Reports in Medicine, 2009 Although hepatic dysfunction is common in adult-onset Still's disease (AOSD), sometimes it is difficult to differentiate hepatic dysfunction due to AOSD itself from drug-induced hepatic dysfunction.
Hidekatsu Yanai +3 more
doaj +1 more source
Rare, rarer, lung involvement in adult-onset Still's disease: A mini-review
Frontiers in Medicine, 2022 Adult-onset Still's disease (AOSD) is a polygenic systemic autoinflammatory disease which is associated with increased morbidity and mortality. Pulmonary involvement is a rare, but serious complication of AOSD. As in AOSD, IL-1b, IL-18, and IL-6 dominate
Jasper F. Nies +2 more
doaj +1 more source
Adult-Onset Still's Disease: A Rare Cause of Pyrexia of Unknown Origin (Case Report with Literature Review) [PDF]
Liaquat National Journal of Primary CareAdult-onset Still’s disease (AOSD) is a remarkably rare illness. One well-known pathogenic process that results in systemic manifestations is auto-inflammatory disease.
Bushra Ali +5 more
doaj +1 more source
Frontiers in Immunology, 2021 BackgroundInterleukin (IL)-18 is markedly elevated in systemic inflammatory diseases that cause the ‘cytokine storm’ such as adult-onset Still’s disease (AOSD) and hemophagocytic lymphohistiocytosis (HLH).
Toshihiko Shiga +7 more
doaj +1 more source
Journal of Immunology Research, 2021 Increasing evidence indicates a pivotal role of macrophages in innate immunity, which contributes to the pathogenesis of adult-onset Still’s disease (AOSD). Despite the available reviews that summarized the pathogenic role of proinflammatory cytokines in
Po-Ku Chen, Der-Yuan Chen
doaj +1 more source
Adult-Onset Still's Disease(AOSD) With Features Suggestive of Macrophages Activation Syndrome in Young Female: A Rare Case Report From Nepal. [PDF]
Clin Case RepABSTRACT Adult‐onset Still's disease (AOSD) is a rare, multisystem autoinflammatory disorder characterized by a classic triad of fever, evanescent rash, and arthritis with diagnostic challenges. We present a case of a previously healthy 22‐year‐old Nepalese female presented with a 1.5‐month history of progressive bilateral lower limb edema and a 13‐day
Silwal S +3 more
europepmc +2 more sources
Incorporating AOSD to Enhance Model Driven Architecture
Journal of Software Engineering and Applications, 2011 Various software development approaches in the present scenario are best suited for a specific application. The software development strategies include both merits and demerits when talked in terms of generalization. The Model Driven Architecture (MDA) describes software development based on models on various levels of abstraction.
Yashwant Singh +3 more
openaire +2 more sources
Ferritin-induced NETs lead to cytokine storm in AOSD
Nature Reviews Rheumatology, 2023 New research reveals that ferritin has an essential role in neutrophil extracellular trap (NET)-mediated inflammation, and suggests that NETs or the ferritin receptor MSR1 could be targeted for the treatment of adult-onset Still disease.
openaire +2 more sources
Frontiers in Immunology, 2019 Adult-onset Still's disease (AOSD) is a systemic inflammatory disease characterized by cytokine storm. However, a diagnostic test for AOSD in clinical use is yet to be validated.
Qiongyi Hu +15 more
doaj +1 more source