Results 1 to 10 of about 4,265 (70)
Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]
E3S Web of Conferences, 2023 Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein +1 more
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Interleukin 18 in Immune-mediated rheumatic diseases and COVID-19
Научно-практическая ревматология, 2022 Immune-mediated rheumatic diseases (IMRDs), based on the leading mechanisms of pathogenesis, are conditionally classified into autoimmune, autoinflammatory, and «mixed pattern».
E. L. Nasonov, A. S. Avdeeva
doaj +1 more source
Dental Research Journal, 2020 Background: Regarding the prevalence and importance of periodontal disease and the potential of salivary biomarkers for the early diagnosis of these diseases, this study was conducted to compare salivary concentrations of Interleukin-17 (IL-17) and ...
Surena Vahabi +2 more
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Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea [PDF]
Archives of the Balkan Medical Union, 2018 Introduction. Rosacea is a common chronic dermatosis characterized by lesions of open areas of the skin (face) and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines – interleukin‑17A
Maryna V. STOROZHUK, Olha I. DENYSENKO
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EMBO Molecular Medicine, 2021 The inflammasome is a cytosolic multiprotein complex that plays a crucial role in inflammation and cell death. The sensor proteins in the inflammasome complex detect various microbial and endogenous stimuli, leading to subsequent caspase activation.
Daisuke Watanabe +2 more
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Interleukin-18 and interleukin-18 Binding Protein
Frontiers in Immunology, 2013 Interleukin-18 (IL 18) is a member of the IL 1 family of cytokines. Increasing reports have expanded the role of IL 18 in mediating inflammation in animal models of disease using IL 18 deficient mice, neutralization of IL 18 or deficiency in the IL 18 ...
Charles eDinarello +6 more
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Journal of Neuroinflammation, 2010 Interleukin (IL)-18 is a cytokine isolated as an important modulator of immune responses and subsequently shown to be pleiotropic. IL-18 and its receptors are expressed in the central nervous system (CNS) where they participate in neuroinflammatory ...
Sugama Shuei +3 more
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Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation
Frontiers in Immunology, 2020 The NLRC4 inflammasome assembles in response to detection of bacterial invasion, and NLRC4 activation leads to the production of IL-1β and IL-18 together with pyroptosis-mediated cell death.
Yuki Sasaki +7 more
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Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia
Journal of Neuroinflammation, 2012 Background The pleiotropic pro-inflammatory cytokine Interleukin (IL)-18 has been proposed to play a role in schizophrenia, since elevated circulating levels of its protein and altered frequencies of genetic variants in its molecular system are reported ...
Palladino Ilaria +7 more
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Physiological and molecular effects of interleukin-18 administration on the mouse kidney
Journal of Translational Medicine, 2018 Background The cytokine interleukin-18 was originally identified as an interferon-γ-inducing proinflammatory factor; however, there is increasing evidence to suggest that it has non-immunological effects on physiological functions.
Kyosuke Yamanishi +13 more
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