Results 31 to 40 of about 5,291,137 (298)

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

open access: yes, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J.   +17 more
core   +1 more source

Interleukin-18 in Human Milk [PDF]

open access: yesPediatric Research, 2001
We analyzed IL-18 levels of human milk. Colostrum contained significantly higher levels of IL-18 compared with early milk and mature milk. By stepwise multiple linear regression analysis, preterm delivery and pregnancy complications of mothers significantly correlated with high levels of IL-18 in human milk (p = 0.0007 and 0.0018, respectively).
Y, Takahata   +7 more
openaire   +2 more sources

Role of Interleukin-18 in vascular injury: a new pharmacological target for the prevention of restenosis [PDF]

open access: yes, 2006
Background: Studies in humans as well as in animal models suggest that interleukin-18 (IL-18) plays a crucial role in vascular pathologies. IL-18 is a strong predictor of cardiovascular death in angina and is involved in atherotic plaque destabilization.
Grassia, Gianluca
core   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

open access: yes, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M   +23 more
core   +2 more sources

The circulating level of interleukins 6 and 18 in ischemic and idiopathic dilated cardiomyopathy [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2019
Introduction: By aging population, the heart failure and its life-threatening complications have become an enormous issue in public health. Regarding the inflammation as a major contributing pathological factor, the determination of most important ...
Mahdiyar Iravani Saadi   +6 more
doaj   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

open access: yes, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda   +10 more
core   +1 more source

Factors Associated With In Vitro Interferon-gamma Production in Tuberculosis

open access: yesJournal of the Formosan Medical Association, 2011
Macrophage activation assisted by interferon-gamma (IFN-γ) is a primary mechanism by which Mycobacterium tuberculosis is killed, but IFN-γ (production is inhibited in tuberculosis (TB) patients. The production of IFN-γ is influenced by many factors, such
Chung-Chieh Yu   +5 more
doaj   +1 more source

Analytical Value of Cell-Free DNA Based on Alu in Psychiatric Disorders

open access: yesFrontiers in Psychiatry, 2020
Psychiatric disorders impose a huge burden on individuals, families, and society. The Alu repeat sequence is a member of the short interspersed nuclear element (SINE) family of mammalian genomes, however, its expression pattern and role in psychiatric ...
Jing Qi   +3 more
doaj   +1 more source

The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis

open access: yesFrontiers in Immunology, 2023
BackgroundInterleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor, IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathic ...
Sebastien Fauteux-Daniel   +17 more
doaj   +1 more source

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]

open access: yes, 2012
BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.
Thomas, GN   +492 more
core   +1 more source

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