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Inflammasomes as Targets for Adjuvants
Pathogens, 2020 Inflammasomes are an essential part of the innate immune system. They are necessary for the development of a healthy immune response against infectious diseases.
Konstantin Ivanov +2 more
exaly +3 more sources
Antiviral Inflammasomes and How to Find Them [PDF]
VirusesInflammasomes are signaling complexes of the innate immune system that are assembled in distinct sentinel cell types to coordinate inflammation. As demonstrated by the emergence of viral antagonists and evasion mechanisms, inflammasomes are critical to ...
Jennifer Deborah Wuerth +1 more
doaj +2 more sources
Bacterial exotoxins and the inflammasome [PDF]
Frontiers in Immunology, 2015 The inflammasomes are intracellular protein complexes that play an important role in innate immune sensing. Activation of inflammasomes leads to activation of caspase-1 and maturation and secretion of the pro-inflammatory cytokines IL-1β and IL-18.
Allison J. Greaney +2 more
doaj +3 more sources
Inflammasomes and pyroptosis in cancer: mechanisms and therapeutic advances [PDF]
Journal of Hematology & OncologyInflammasomes are being increasingly recognized for their critical roles in regulating immune cell infiltration, antitumor immunity, and tumorigenesis in cancer biology.
Wonhyoung Seo +6 more
doaj +2 more sources
The Role of Inflammasomes in Mediating Urological Disease: A Short Literature Review
Journal of Inflammation Research, 2022 Sarah Shidid +2 more
exaly +3 more sources
Molecular Aspects of Medicine, 2020 Ketelut-Carneiro and Fitzgerald discuss the basic concepts about inflammasome composition, assembly and activation, effector functions and role in infection and inflammatory disease.
Natália, Ketelut-Carneiro +1 more
openaire +4 more sources
Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response
Journal of Advanced Research, 2023 Background: Innate and adaptive immunity are two different parts of the immune system that have different characteristics and work together to provide immune protection. Inflammasomes are a major part of the innate immune system that are expressed widely
Hongliang Zhang +4 more
doaj +1 more source
Roles of inflammasomes in viral myocarditis
Frontiers in Cellular and Infection Microbiology, 2023 Viral myocarditis (VMC), characterized by viral infection-induced inflammation, is a life-threatening disease associated with dilated cardiomyopathy or heart failure.
Jingyu Xu +5 more
doaj +1 more source
The roles of inflammasomes in cancer
Frontiers in Immunology, 2023 Inflammation is a key characteristic of all stages of tumor development, including tumor initiation, progression, malignant transformation, invasion, and metastasis.
Zihan Deng +5 more
doaj +1 more source