Results 1 to 10 of about 98,903 (118)
S-Nitrosoglutathione protects acute kidney injury in septic rats by inhibiting the activation of NLRP3 inflammasome [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): We aimed to study the effect of S-nitroso glutathione (SNG) on acute kidney injury (AKI) in septic rats by regulating nucleotide oligomerization domain-like receptor protein 3 (NLRP3).Materials and Methods: Sprague Dawley rats were used to ...
Heng Fan +3 more
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Effects of three types of fresh Rehmannia glutinosa improve lipopolysaccharide-induced acute kidney injury in sepsis through the estrogen receptor pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): To explore the effects and mechanism of three types of fresh Rehmannia glutinosa, namely Beijing No. 3 (BJ3H), Huaizhong No. 1 (HZ1H), and Taisheng (TS) on lipopolysaccharide (LPS)-induced acute kidney injury in the sepsis (S-AKI) mice ...
Meng Liu +11 more
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Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells
Cells, 2020 Schizophrenia is a complex psychiatric disorder that exhibits an interconnection between the immune system and the brain. Experimental and clinical studies have suggested the presence of neuroinflammation in schizophrenia.
Vijayasree V. Giridharan +9 more
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Archives of Pharmaceutical Sciences Ain Shams University, 2023 Background: Breast cancer (BC) is considered the main cause of death in women worldwide. Overexpression of Sphingosine 1-phosphate (S1P) receptors in estrogen receptor (ER) negative BC patients is linked to poor prognosis.
Anas R. Soltan +3 more
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Pyroptosis: A New Regulating Mechanism in Cardiovascular Disease
Journal of Inflammation Research, 2021 Nan Ji,1,2,* Zhongwen Qi,1,* Yueyao Wang,1 Xiaoya Yang,1 Zhipeng Yan,1 Meng Li,1 Qihui Ge,1 Junping Zhang1 1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300183, People’s Republic of China; 2National ...
Ji N +7 more
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Diabetes, Metabolic Syndrome and Obesity, 2021 Tianyu Meng,1,* Jie Wang,2,3,* Manyun Tang,2 Shangyu Liu,4 Ligang Ding,4 Yang Yan5 1Department of Geriatrics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Department of
Meng T +5 more
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Inflammasome as an Effective Platform for Fibrosis Therapy
Journal of Inflammation Research, 2021 Ting-Ting Chen,* Feng Xiao,* Nan Li, Shan Shan, Meng Qi, Zi-Ying Wang, Sheng-Nan Zhang, Wei Wei, Wu-Yi Sun Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui
Chen TT +8 more
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NLRP3 and CARD8 polymorphisms influence higher disease activity in rheumatoid arthritis [PDF]
Journal of Medical Biochemistry, 2016 Background: The activation of NLRP3-inflammasome may contribute to inflammatory processes in rheumatoid arthritis (RA). Functional polymorphisms in the genes coding for its components NLRP3 and CARD8 were associated with a proinflammatory phenotype.
Jenko Barbara +3 more
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Frontiers in Bioscience-Landmark, 2023 Background: Myasthenia gravis (MG) is an autoantibodies-mediated autoimmune disease with the complications of neuromuscular junction transmission. In this study, we aimed to investigate the molecular regulatory roles of pentaxin 3 (PTX3) in patients and ...
Yao Li +3 more
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Journal of Inflammation Research, 2021 Zhi-He Liu,1 Lin Zhang,2 Fan-Jing Jing,1 Shu-Xin Xiao,1 Yan Gao,1 Hai-Yan Bian,1 Xia Zhao1 1Department of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, People’s Republic of China; 2Laboratory of Molecular Diagnosis
Liu ZH +6 more
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