Results 31 to 40 of about 120,852 (299)
Spotlight on the NLRP3 inflammasome pathway
, 2018 Marine Groslambert,1–5 Bénédicte F Py1–5 1Centre International de Recherche en Infectiologie (CIRI), Université de Lyon, Lyon, France; 2INSERM, U1111, Lyon, France; 3Ecole Normale Supérieure de Lyon, Lyon, France ...
Py BF, Groslambert M
core +2 more sources
Frontiers in Bioscience-LandmarkSubarachnoid hemorrhage (SAH), a severe cerebrovascular disorder, is principally instigated by the rupture of an aneurysm. Early brain injury (EBI), which gives rise to neuronal demise, microcirculation impairments, disruption of the blood-brain barrier,
Xi Zhang +6 more
doaj +1 more source
Pathological Mechanism and Targeted Drugs of COPD
International Journal of COPD, 2022 Peng Guo,1 Rui Li,2 Tie Hua Piao,3 Chun Lan Wang,3 Xiao Lu Wu,3 Hong Yan Cai3 1College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Changchun, 130000, People’s Republic of China; 2Graduate School, Beijing ...
Guo P +5 more
doaj
Journal of Inflammation Research, 2022 Jesús Beltrán-García,1– 3 Rebeca Osca-Verdegal,1,3 Daniel Pérez-Cremades,2,3 Susana Novella,2,3 Carlos Hermenegildo,2,3 Federico V Pallardó,1– 3 José Luis García-Giménez1– 3 1Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER ...
Beltrán-García J +6 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Drug Design, Development and Therapy, 2020 Cancan Huang, Chaotao Zhang, Panpan Yang, Rui Chao, Ziqi Yue, Congshan Li, Jie Guo, Minqi Li Department of Bone Metabolism, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue ...
Huang C +7 more
doaj
Journal of Inflammation Research, 2021 Ning Li,* Rui Xiong,* Ruyuan He, Bohao Liu, Bo Wang, Qing Geng Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bo Wang ...
Li N +5 more
doaj
, 2022 reservedLa malattia di Alzheimer, una delle forme di demenza più comuni, sta diventando sempre più predominante a causa dell’allungamento della vita. È stato osservato che, oltre all’invecchiamento, anche il processo neuroinfiammatorio cronico ha un ...
MARINUZZI, NATALE LUCA
core
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Role of Pyroptosis in Diabetes and Its Therapeutic Implications
Journal of Inflammation Research, 2021 Abdullah Al Mamun,1 Yanqing Wu,2 Fatema Nasrin,3,4 Afroza Akter,5 Masuma Afrin Taniya,6 Fahad Munir,7 Chang Jia,8 Jian Xiao1 1Department of Hand Surgery and Peripheral Neurosurgery, The First Affiliated Hospital and School of Pharmaceutical Sciences ...
Al Mamun A +7 more
doaj