Results 11 to 20 of about 613,671 (263)

Interleukin-18 in Inflammatory Kidney Disease [PDF]

Frontiers in Medicine, 2021
Interleukin (IL)-18, a member of the IL-1 superfamily, is a pro-inflammatory cytokine that is structurally similar to IL-1β. IL-18 promotes the production of interferon gamma (IFN-γ) and strongly induces a Th1 response.
Yasuaki Hirooka, Yuji Nozaki
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Serum interleukin 18 level in kidney diseases and age [PDF]

Urology Annals
Background: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene, it is a member of the IL 1 family and has a molecular weight of 18 kDa.
Ghada Abd Eltawab Radwan, Ali El-Said Yousef, Mohamed Fathy Bayomy   +2 more
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Interleukin-18 [PDF]

Journal of Leukocyte Biology, 2003
Abstract Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases ...
Gracie, J.A., Robertson, S.E., McInnes, I.B.   +2 more
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Interleukin-18 and COVID-19 [PDF]

Epidemiology and Infection, 2021
Abstract Vulnerability to coronavirus disease (COVID)-19 varies due to differences in interferon gamma (IFNγ) immunity. We investigated whether a key modifiable interferon precursor, interleukin-18, was related to COVID-19, overall and by severity, using Mendelian randomisation.
C. M. Schooling, M. Li, S. L. Au Yeung
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Interleukin-18

International Heart Journal, 2018
A prospective observational study was conducted to evaluate the predictive value of interleukin-18 (IL-18) for major adverse cardiovascular events (MACEs) in hemodialysis patients. A total of 85 participants (45 hemodialysis patients and 40 healthy volunteers) with a mean age of 56.3 years were enrolled in this study. Demographic and clinical data were
Wang, Shiying, Chen, Fang, Yang, Suxia, Shi, Jun   +3 more
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Targeting interleukin 18 with interleukin 18 binding protein [PDF]

Annals of the Rheumatic Diseases, 2000
A novel, constitutively expressed and secreted interleukin 18 (IL18) binding protein (IL18BP) neutralises IL18. IL18BP shares many characteristics with soluble cytokine receptors of the IL1 family in that the protein exhibits specificity for IL18, belongs to the immunoglobulin-like class of receptors and has limited amino acid sequences with those of ...
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Serum interleukin 18 and interleukin 18 binding protein in rheumatoid arthritis [PDF]

Annals of the Rheumatic Diseases, 2002
To measure serum interleukin 18 (IL18) and IL18 binding protein (IL18BP) levels in patients with inflammatory arthropathies, and to identify associations with disease status and the response to treatment.Serum samples were obtained before and after methotrexate treatment from patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA ...
B, Bresnihan, P, Roux-Lombard, E, Murphy, D, Kane, O, FitzGerald, J-M, Dayer   +5 more
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Interleukin-18 and interleukin-18 receptor-α expression in allergic asthma [PDF]

European Respiratory Journal, 2011
To the Editors: The inflammatory process in allergic asthma is initiated by T-helper (Th) type-2 cells, which produce a repertoire of cytokines, including interleukin (IL)-4, IL-5, IL-9 and IL-13, which are necessary for immunoglobulin (Ig)E production, airway eosinophilia and goblet cell hyperplasia [1].
H, Imaoka, G M, Gauvreau, R M, Watson, S G, Smith, B, Dua, A J, Baatjes, K, Howie, T, Hoshino, K J, Killian, H, Aizawa, P M, O'Byrne   +10 more
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Increased Expression of Interleukin-18 mRNA is Associated with Carotid Artery Stenosis

Balkan Medical Journal, 2018
Background: Carotid artery stenosis is the atherosclerotic narrowing of the proximal internal carotid artery and one of the primary causes of stroke. Elevated expression of the pleiotropic proinflammatory cytokine interleukin-18 has been demonstrated in ...
Berk Arapi, Burcu Bayoğlu, Müjgan Cengiz, Ahmet Dirican, Serkan Burç Deser, Yerik Junusbekov, Caner Arslan   +6 more
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Diagnostic values of serum IL-17A and IL-18 in Rheumatoid arthritis and Correlation with treatment

مجلة مركز بحوث التقنيات الاحيائية, 2022
Background: Rheumatoid arthritis (RA) is an autoimmune disorder that involves autoantibodies attacking and weakening joints. RA is characterized by leukocyte (Monocyte, Lymphocyte mast cell .etc) infiltrations into the synovial compartment leading to ...
Noorhan H. Yousif, Shaima R. Ibraheem , Aseel shakir Mahmood   +2 more
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