Abstract Background Coping behavior of Parkinson's disease (PD) patients undergoing subthalamic Deep Brain Stimulation (STN‐DBS) is poorly understood. Identifying patients with ineffective coping could help prepare them better for surgery. Objectives To clarify coping of PD patients preoperatively and the relation with psychiatric symptoms, quality of ...
Roy Brian Kuiper +8 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Monoaminergic Networks of Cognitive and Behavioral Symptoms in Early Parkinson's Disease
Abstract Background Parkinson's disease (PD) is associated with several behavioral and cognitive symptoms, the neurobiological background of which is not yet fully understood. Objectives The aim was to investigate the association between monoamine function and four specific nonmotor symptoms in early PD using the Parkinson's Progression Markers ...
Kalle J. Niemi +3 more
wiley +1 more source
Abstract Background Neuropsychological deficits have been observed in patients with cerebellar damage, but never thoroughly investigated in autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS). Objectives The goal is the characterization of presence, severity, and profile of neuropsychological deficits in ARSACS using the cerebellar ...
Julie Fortin +11 more
wiley +1 more source
Early Autonomic Burden in Prodromal Parkinson's Disease Predicts Cognitive Impairment
Abstract Background Autonomic dysfunction is a known contributor to cognitive impairment in Parkinson's disease (PD), but its impact during prodromal stage is unknown. Objective The aim was to determine whether early autonomic burden predicts incident cognitive impairment in prodromal PD.
A. Enrique Martinez‐Nunez +5 more
wiley +1 more source
Procrastination as a marker of cognitive decline: Evidence from longitudinal transitions in the older adult population. [PDF]
Monaghan C +3 more
europepmc +1 more source
Validation of the German Version of the Movement Disorder Society Non‐Motor Scale (MDS‐NMS)
Movement Disorders Clinical Practice, EarlyView.
Jonas Bendig +20 more
wiley +1 more source
Psychiatric Disorders and Apathy in Mixed Movement Disorders Linked to ADCY5 (MxMD‐ADCY5)
Abstract Background Mixed movement disorders linked to ADCY5 (MxMD‐ADCY5) represent a rare hyperkinetic movement disorder resulting from pathogenic variants in ADCY5. Psychiatric symptoms are suspected to be part of the phenotype. Objective The study aim was to assess psychiatric comorbidities in patients with MxMD‐ADCY5.
Aurélie Méneret +23 more
wiley +1 more source
When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions
Abstract Although Parkinson's disease (PD) is classically defined by its motor features, non‐motor symptoms exert a substantial and often under‐recognized influence on disease trajectory. Among these, weight loss has long been observed in PD and other neurodegenerative disorders, yet the mechanisms remain incompletely understood.
Ellie D. Gabriel +6 more
wiley +1 more source
From mild behavioral impairment-checklist (MBI-C) to MBI-distress (MBI-D): a paired assessment and clinical correlates of domain-specific caregiver distress in MCI due to AD. [PDF]
Angelopoulou E +9 more
europepmc +1 more source

