Results 221 to 230 of about 158,301 (286)

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera   +6 more
wiley   +1 more source

Novel syngeneic model of anti-mouse CLDN18.2 CAR -T therapy for gastric cancer demonstrates a synergy with TGF-β and PD-L1 inhibitors. [PDF]

open access: yesMol Ther Oncol
Seo MJ   +12 more
europepmc   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev   +7 more
wiley   +1 more source

Selective RyR2 inhibition reduces arrhythmia susceptibility in human cardiac slices

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ent‐Vert selectively inhibits RyR2‐mediated sarcoplasmic reticulum (SR) Ca2+ leak and prevents triggered activity in human cardiac slices. A, in human ventricular slices exposed to β‐adrenergic stimulation with Iso and RyR2 sensitization with caffeine, RyR2 channels become hyperactive, leading to Ca2+ sarcoplasmic leak and ...
Micah K. Madrid   +6 more
wiley   +1 more source

Multiple ortho‐mosaicking software pipelines produce comparable imagery‐derived wheat phenotypes

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Unmanned aerial systems (UAS) equipped with multispectral and RGB sensors offer valuable data for monitoring crop health and assessing disease severity. However, the wide range of available photogrammetric software complicates software selection for high‐throughput plant phenotyping.
Sanju Shrestha   +3 more
wiley   +1 more source

In Support of APD

open access: yesThe ASHA Leader, 2017
openaire   +1 more source

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