Results 221 to 230 of about 187,448 (328)

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Clinical analysis of laparoscopic pyeloplsty for ureteropelvic junction obstruction in infants under 3 months old. [PDF]

Front Pediatr
Bian Z, Xiong G, Liu T, Zhi Y, Liu M.
europepmc   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

Anti-PD-L1-IFN-α-adjuvanted HBsAg vaccine overcomes HBV immune tolerance through targeting both DCs and macrophages. [PDF]

JCI Insight
Meng CY, Liang Y, Xu L, Li H, Guo J, Xu H, Wang F, Fu YX, Peng H.   +8 more
europepmc   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

The Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer, Edward J. Vigmond, Ruben Coronel, Chantal E. Conrath   +3 more
wiley   +1 more source

High-dose treatment of cathepsin B-activatable doxorubicin prodrug nanoparticles that induce tumor-specific immunogenic cell death for immunotherapy of melanoma with minimal systemic toxicity. [PDF]

Asian J Pharm Sci
Oh Y, Kim J, Shim N, Yoo H, Lee H, Jeong Y, Goo J, Lee J, Jo M, Cho H, Kim K.   +10 more
europepmc   +1 more source

APD Diagnosis

, 2018
Kiese-Himmel, Christiane, Gross, M.
openaire   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

Predictive value of internal jugular vein combining with inferior vena cava diameters by ultrasound in central venous pressure of ICU patients. [PDF]

Sci Rep
Kong H, Zhang Z, Shen D, Li Y, Zhang Y.
europepmc   +1 more source