Results 41 to 50 of about 23,795 (166)

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

Extraction of Antimicrobial Peptides From Fava Bean Protein Hydrolyzate by Phosphorylated Biochar

Food Safety and Health, EarlyView.
Antimicrobial peptides were extracted by functional biochar in one step. The enriched peptides demonstrated significantly enhanced antibacterial activity. ABSTRACT The extraction of antimicrobial peptides (AMPs) from plant proteins remains challenging due to their low abundance, structural diversity, and the need for mild, efficient, and selective ...
Xiang‐Yu Huang, Hao‐Ran Liu, Rong Guo, Li Ding, Li Wen, Xu‐Feng Wang, Zhou Xu, Yun‐Hui Cheng, Mao‐Long Chen   +8 more
wiley   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

Trajectory of irritability in children and youth in Ontario, Canada, throughout the COVID‐19 pandemic

JCPP Advances, EarlyView.
This study explored how irritability in children and youth changed during the COVID‐19 pandemic and its impact on mental health. Results showed a gradual decline in irritability, with factors like age, parental anxiety, and resilience influencing its trajectory.
Theodore C. K. Cheung, Katherine T. Cost, Ronda F. Lo, Evdokia Anagnostou, Catherine S. Birken, Alice Charach, Suneeta Monga, Elizabeth Kelley, Rob Nicolson, Paul D. Arnold, Christie Burton, Daphne J. Korczak, Jennifer Crosbie   +12 more
wiley   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

Sewage Sludge and Cashew Bagasse Biochars Promote Changes in Selected Physical Attributes Related to the Structure of Degraded Dryland Soil

Journal of Plant Nutrition and Soil Science, EarlyView.
This study evaluated biochars from co‐pyrolysis of sewage sludge and cashew residues on physical quality of a degraded loamy sand soil. SPB applied at 20 Mg ha−1 reduced bulk density by 7.74%, whereas most porosity attributes were driven by soil reconsolidation rather than biochar. Aggregate stability varied with biochar type, with SPB promoting larger
João Marcos Rodrigues dos Santos, Ícaro Vasconcelos do Nascimento, Gilvanete da Silva Henrique, Tiago da Costa Dantas Moniz, Francisco Luan Almeida Barbosa, Alexandre dos Santos Queiroz, Adriana Guirado Artur, Mirian Cristina Gomes Costa, Helon Hébano de Freitas Sousa, Odair Pastor Ferreira, Laís Gomes Fregolente, Antônio Gomes de Souza Filho, Romildo Lopes de Oliveira Filho, Arthur Prudêncio de Araujo Pereira, Jaedson Cláudio Anunciato Mota   +14 more
wiley   +1 more source

Ohmic heating dominates and ultrasound modulates aquafaba structure: A combined approach to design stable plant‐based emulsions

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study investigated the individual and combined effects of ohmic heating (OH, 20 and 40 V cm−1) and ultrasound (US, 425 and 850 W) on the chemical, physicochemical, and technological properties of chickpea aquafaba (AF) and its emulsions.
Débora Krichanã, Thaís Caroline Buttow Rigolon, Paula Zambe Azevedo, João Paulo de Melo Lins, Gabriel Oliveira Horta, Linamarys Aparecida de Oliveira Paulo, Márcia Cristina Teixeira Ribeiro Vidigal, Taline Amorim Santos, Isis Rodrigues Toledo Renhe, Jaqueline de Araújo Bezerra, Paulo César Stringheta, Evandro Martins, Pedro Henrique Campelo   +12 more
wiley   +1 more source

Abduction and adduction malpositioned lateral radiographs cannot be used for proper assessment of the posterior tibial slope

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare medial posterior tibial slope (mPTS) measurements on abduction/adduction malpositioned versus properly positioned lateral knee radiographs within the same patients. We hypothesized that malpositioning would significantly alter mPTS values and potentially change surgical classification at the commonly used 12° threshold for ...
Moses Kamal Dieter El Kayali, Luis Vincent Bürck, Stephen Fahy, Alan Getgood, Clemens Gwinner, Lorenz Pichler   +5 more
wiley   +1 more source

Posterior tibial slope measurement on lateral radiographs shows increased variability, reduced repeatability and risk of misclassification in osteoarthritic versus nonosteoarthritic knees

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The primary aim was to compare the variability and repeatability of medial posterior tibial slope (MPTS) measurements on lateral knee radiographs between osteoarthritic (OA) and non‐OA knees, and the secondary aim was to assess their implications for clinical classification.
Moses Kamal Dieter El Kayali, Luis Vincent Bürck, Clemens Gwinner, Lorenz Pichler, Alan Getgood, Mo Saffarini, Rosa Berndt   +6 more
wiley   +1 more source