Results 71 to 80 of about 49,952 (301)

Relationship of Substance Use Disorder to Aggression in Male Subjects with Antisocial Personality Disorder [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2007
Objective: Aggression is a particular problem commonly observed in personality disorders, especially in antisocial personality disorder (APD). It is well known that APD is closely related to substance use disorder (SUD).
Ayhan Algül, Ümit Başar Semiz, M. Alpay Ateş, Cengiz Başoğlu, Ali Doruk, Servet Ebrinç, Erdal Pan, Mesut Çetin   +7 more
doaj  

Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. [PDF]

PLoS ONE, 2014
Prolongation of action potential duration (APD), increased spatial APD dispersion, and triangulation are major factors promoting drug-induced ventricular arrhythmia. Preclinical identification of HERG/IKr-blocking drugs and their pro-arrhythmic potential,
David Ziupa, Julia Beck, Gerlind Franke, Stefanie Perez Feliz, Maximilian Hartmann, Gideon Koren, Manfred Zehender, Christoph Bode, Michael Brunner, Katja E Odening   +9 more
doaj   +1 more source

Investigating the plastic decomposing ability of Tenebrio molitor using carbon dioxide sensors

, 2021
According to a group of Stanford scientists, mealworms, the larva of darkling beetles, can digest Styrofoam, a type of polystyrene, and break it down into carbon dioxide.
Huang, Xiangrong, Lim, Kenneth Yang Teck, Li, Yueyi   +2 more
core  

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Regional differences in APD restitution can initiate wavebreak and re-entry in cardiac tissue: A computational study

BioMedical Engineering OnLine, 2005
Background Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood.
Taggart Peter, Clayton Richard H
doaj   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Single–Atom Iron Sites Enable Enhanced Arsenic Removal From Water Through Synergistic Adsorption–Oxidation

Advanced Science, EarlyView.
Single–atom iron anchored on nitrogen–doped porous biochar exhibited ultra–efficient performance, exceptional environmental resilience, and integrated adsorption–oxidation functionality. The multifunctional architecture of the support and the unparalleled reactivity of single–atom iron underpinned the cooperative adsorption and oxidation of As(III ...
Tao Sun, Chao Wang, Shihang Wu, Xiaojia Zhou, Penggang Pei, Huijuan Yu, Yun Zhang, Qingqing Huang, Yuebing Sun   +8 more
wiley   +1 more source

AusTraits Plant Dictionary (APD)

<p>The Austraits Plant Dictionary (APD) offers detailed descriptions for more than 500 plant trait concepts.</p><p>APD includes trait focused on plant morphology, plant nutrient concentrations, plant physiology, plant life history, and ...
Gallagher, Rachael, Boettiger, Carl, Sauquet, Hervé, Brownlee, Rowan, Falster, Daniel, Wenk, Elizabeth   +5 more
core   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source