Results 261 to 270 of about 23,711 (313)

Click-Functionalized Cyanine Fluorogenic Dimers for Improved Detection of GPCRs: Application to Imaging of ApelinR in Living Cells. [PDF]

open access: yesChemistry
Florès O   +10 more
europepmc   +1 more source

A Metabolically Stable Apelin-13 Analog Acting as a Potent I<sub>To</sub> Potassium Current Blocker with Potential Benefits for Brugada Syndrome. [PDF]

open access: yesInt J Mol Sci
Contreras Vite JA   +8 more
europepmc   +1 more source
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The exerkine apelin reverses age-associated sarcopenia

Nature Medicine, 2018
Umji Lee, anne Bigot, Vincent Mouly
exaly   +2 more sources

Elabela/Toddler and apelin bind differently to the apelin receptor [PDF]

open access: possibleThe FASEB Journal, 2020
Like apelin (pE13F, K17F), Elabela/Toddler is an endogenous ligand of the apelin receptor playing a key role in cardiovascular development. Elabela/Toddler exists as peptide fragments of 32 (Q32P), 22 (K22P) and 11 (C11P) amino acids. In this study, we investigated the possible structural and functional similarities between these endogenous ligands. We
Xavier Iturrioz   +2 more
openaire   +2 more sources

Presence and expression of apelin and apelin receptor in bitch placenta

Theriogenology, 2020
Apelin is a potent inotropic agent causing endothelium-mediated vasodilation and is involved in vessel formation by interacting with a specific receptor. Its cardiovascular profile suggests a role in the regulation of gestational hemodynamic changes. The expression of apelin and its receptor has been reported in some portions of the reproductive tract ...
Troisi A.   +6 more
openaire   +4 more sources

Apelin, diabetes, and obesity

Endocrine, 2011
Apelin is a peptide known as the ligand of the G-protein-coupled receptor APJ. Several active apelin forms exist such as apelin-36, apelin-17, apelin-13, and the pyroglutamated form of apelin-13. Apelin and APJ are expressed in the central nervous system, particularly in the hypothalamus and in many peripheral tissues.
Isabelle Castan-Laurell   +2 more
exaly   +4 more sources

Roles of apelin/APJ system in cancer: Biomarker, predictor, and emerging therapeutic target

Journal of Cellular Physiology, 2022
Cancer is a disease that seriously endangers human health and is mainly characterized by a high metastasis rate, a high recurrence rate, and a high mortality rate.
Jiawei Chen   +3 more
semanticscholar   +1 more source

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